Exploring the biological basis of deficiency pattern in rheumatoid arthritis through text mining

Guang Zheng; Miao Jiang; Cheng Lu; Hongtao Guo; Junping Zhan; Aiping Lu

doi:10.1109/BIBMW.2011.6112477

Exploring the biological basis of deficiency pattern in rheumatoid arthritis through text mining

Guang Zheng
, Miao Jiang
, Cheng Lu
, Hongtao Guo
, Junping Zhan
, Aiping Lu^*

^*Corresponding author for this work

Office of the Dean of Chinese Medicine

Research output: Chapter in book/report/conference proceeding › Conference proceeding › peer-review

11 Citations (Scopus)

Abstract

In the theory of traditional Chinese medicine, deficiency pattern is a distinguished one among patterns in rheumatoid arthritis. As for the explanation of deficiency pattern in rheumatoid arthritis, traditional Chinese medicine explains the deficiency in organs of both liver and kidney. As for the modern medicine, no specific factor available to explain it. In this paper, we propose an approach through data mining to explore the biological basis of deficiency pattern in rheumatoid arthritis. In this approach, the first step is to find the formula in traditional Chinese medicine in the treatment of rheumatoid arthritis. Then, list out the top three diseases which can be regulated by this formula. After that, we can find the networks of biological basis existing among all these three diseases by data mining. By analyzing these networks, directly or not, the deficiency pattern in rheumatoid arthritis might be caused by the chronic inflammation.

Original language	English
Title of host publication	2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011
Editors	Brian Chen, Jake Chen, Xin Chen, Yidong Chen, Young-Rae Cho, Juan Cui, Nurit Haspel, Jing He, Hui-Huang Hsu, Yufei Huang, Kun Huang, Rui Jiang, Yury Khudyakov, Chee Keong Kwoh, Guojun Li, Guo-Zheng Li, Ion Mandoiu, Taesung Park, Alberto Policriti, Zhaohui Steve Qin, Chandan Reddy, Habtom Ressom, Glen Satten, Christian Schönbach, Amarda Shehu, Min Song, Xiaofeng Song, Vincent Tseng, Zunyan Xiong, Illhoi Yoo, Alex Zelikovsky, Guanglan Zhang, Joe Zhang, Shaying Zhao, Zhongming Zhao, Jane Zheng, Dongxiao Zhu
Place of Publication	California
Publisher	IEEE
Pages	811-816
Number of pages	6
ISBN (Electronic)	9781457716133
ISBN (Print)	9781457716126
DOIs	https://doi.org/10.1109/BIBMW.2011.6112477
Publication status	Published - 12 Nov 2011
Event	2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops - Atlanta, GA, United States Duration: 12 Nov 2011 → 15 Nov 2011 https://ieeexplore.ieee.org/xpl/conhome/6105661/proceeding (Conference proceeding)

Publication series

Name	IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW

Conference

Conference	2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops
Abbreviated title	BIBMW 2011
Country/Territory	United States
City	Atlanta, GA
Period	12/11/11 → 15/11/11
Internet address	https://ieeexplore.ieee.org/xpl/conhome/6105661/proceeding (Conference proceeding)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

User-Defined Keywords

biological basis
chronic inflammation
deficiency pattern
rheumatoid arthritis
text mining

Access to Document

10.1109/BIBMW.2011.6112477

Cite this

Zheng, G., Jiang, M., Lu, C., Guo, H., Zhan, J., & Lu, A. (2011). Exploring the biological basis of deficiency pattern in rheumatoid arthritis through text mining. In B. Chen, J. Chen, X. Chen, Y. Chen, Y.-R. Cho, J. Cui, N. Haspel, J. He, H.-H. Hsu, Y. Huang, K. Huang, R. Jiang, Y. Khudyakov, C. K. Kwoh, G. Li, G.-Z. Li, I. Mandoiu, T. Park, A. Policriti, Z. S. Qin, C. Reddy, H. Ressom, G. Satten, C. Schönbach, A. Shehu, M. Song, X. Song, V. Tseng, Z. Xiong, I. Yoo, A. Zelikovsky, G. Zhang, J. Zhang, S. Zhao, Z. Zhao, J. Zheng, ... D. Zhu (Eds.), 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011 (pp. 811-816). (IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW). IEEE. https://doi.org/10.1109/BIBMW.2011.6112477

Zheng, Guang ; Jiang, Miao ; Lu, Cheng et al. / Exploring the biological basis of deficiency pattern in rheumatoid arthritis through text mining. 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. editor / Brian Chen ; Jake Chen ; Xin Chen ; Yidong Chen ; Young-Rae Cho ; Juan Cui ; Nurit Haspel ; Jing He ; Hui-Huang Hsu ; Yufei Huang ; Kun Huang ; Rui Jiang ; Yury Khudyakov ; Chee Keong Kwoh ; Guojun Li ; Guo-Zheng Li ; Ion Mandoiu ; Taesung Park ; Alberto Policriti ; Zhaohui Steve Qin ; Chandan Reddy ; Habtom Ressom ; Glen Satten ; Christian Schönbach ; Amarda Shehu ; Min Song ; Xiaofeng Song ; Vincent Tseng ; Zunyan Xiong ; Illhoi Yoo ; Alex Zelikovsky ; Guanglan Zhang ; Joe Zhang ; Shaying Zhao ; Zhongming Zhao ; Jane Zheng ; Dongxiao Zhu. California : IEEE, 2011. pp. 811-816 (IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW).

@inproceedings{6c67a14020df45138d29ce361f8939ee,

title = "Exploring the biological basis of deficiency pattern in rheumatoid arthritis through text mining",

abstract = "In the theory of traditional Chinese medicine, deficiency pattern is a distinguished one among patterns in rheumatoid arthritis. As for the explanation of deficiency pattern in rheumatoid arthritis, traditional Chinese medicine explains the deficiency in organs of both liver and kidney. As for the modern medicine, no specific factor available to explain it. In this paper, we propose an approach through data mining to explore the biological basis of deficiency pattern in rheumatoid arthritis. In this approach, the first step is to find the formula in traditional Chinese medicine in the treatment of rheumatoid arthritis. Then, list out the top three diseases which can be regulated by this formula. After that, we can find the networks of biological basis existing among all these three diseases by data mining. By analyzing these networks, directly or not, the deficiency pattern in rheumatoid arthritis might be caused by the chronic inflammation.",

keywords = "biological basis, chronic inflammation, deficiency pattern, rheumatoid arthritis, text mining",

author = "Guang Zheng and Miao Jiang and Cheng Lu and Hongtao Guo and Junping Zhan and Aiping Lu",

note = "This work was partially supported by the National Eleventh Five Year Support Project of China (2006BAI04A10), the Innovative Methodology Project supported by MOST of China (2008IM020900). National Science Foundation of China (No. 30902003, 30973975, 90709007, and 81072982). China Postdoctoral Science Foundation (No. 20110940553) Publisher Copyright: {\textcopyright}2011 by the Institute of Electrical and Electronics Engineers. All rights reserved; 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011 ; Conference date: 12-11-2011 Through 15-11-2011",

year = "2011",

month = nov,

day = "12",

doi = "10.1109/BIBMW.2011.6112477",

language = "English",

isbn = "9781457716126",

series = "IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW",

publisher = "IEEE",

pages = "811--816",

editor = "Brian Chen and Jake Chen and Xin Chen and Yidong Chen and Young-Rae Cho and Juan Cui and Nurit Haspel and Jing He and Hui-Huang Hsu and Yufei Huang and Kun Huang and Rui Jiang and Yury Khudyakov and Kwoh, \{Chee Keong\} and Guojun Li and Guo-Zheng Li and Ion Mandoiu and Taesung Park and Alberto Policriti and Qin, \{Zhaohui Steve\} and Chandan Reddy and Habtom Ressom and Glen Satten and Christian Sch{\"o}nbach and Amarda Shehu and Min Song and Xiaofeng Song and Vincent Tseng and Zunyan Xiong and Illhoi Yoo and Alex Zelikovsky and Guanglan Zhang and Joe Zhang and Shaying Zhao and Zhongming Zhao and Jane Zheng and Dongxiao Zhu",

booktitle = "2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011",

address = "United States",

url = "https://ieeexplore.ieee.org/xpl/conhome/6105661/proceeding",

}

Zheng, G, Jiang, M, Lu, C, Guo, H, Zhan, J & Lu, A 2011, Exploring the biological basis of deficiency pattern in rheumatoid arthritis through text mining. in B Chen, J Chen, X Chen, Y Chen, Y-R Cho, J Cui, N Haspel, J He, H-H Hsu, Y Huang, K Huang, R Jiang, Y Khudyakov, CK Kwoh, G Li, G-Z Li, I Mandoiu, T Park, A Policriti, ZS Qin, C Reddy, H Ressom, G Satten, C Schönbach, A Shehu, M Song, X Song, V Tseng, Z Xiong, I Yoo, A Zelikovsky, G Zhang, J Zhang, S Zhao, Z Zhao, J Zheng & D Zhu (eds), 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW, IEEE, California, pp. 811-816, 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, Atlanta, GA, United States, 12/11/11. https://doi.org/10.1109/BIBMW.2011.6112477

Exploring the biological basis of deficiency pattern in rheumatoid arthritis through text mining. / Zheng, Guang; Jiang, Miao; Lu, Cheng et al.
2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. ed. / Brian Chen; Jake Chen; Xin Chen; Yidong Chen; Young-Rae Cho; Juan Cui; Nurit Haspel; Jing He; Hui-Huang Hsu; Yufei Huang; Kun Huang; Rui Jiang; Yury Khudyakov; Chee Keong Kwoh; Guojun Li; Guo-Zheng Li; Ion Mandoiu; Taesung Park; Alberto Policriti; Zhaohui Steve Qin; Chandan Reddy; Habtom Ressom; Glen Satten; Christian Schönbach; Amarda Shehu; Min Song; Xiaofeng Song; Vincent Tseng; Zunyan Xiong; Illhoi Yoo; Alex Zelikovsky; Guanglan Zhang; Joe Zhang; Shaying Zhao; Zhongming Zhao; Jane Zheng; Dongxiao Zhu. California: IEEE, 2011. p. 811-816 (IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW).

Research output: Chapter in book/report/conference proceeding › Conference proceeding › peer-review

TY - GEN

T1 - Exploring the biological basis of deficiency pattern in rheumatoid arthritis through text mining

AU - Zheng, Guang

AU - Jiang, Miao

AU - Lu, Cheng

AU - Guo, Hongtao

AU - Zhan, Junping

AU - Lu, Aiping

N1 - This work was partially supported by the National Eleventh Five Year Support Project of China (2006BAI04A10), the Innovative Methodology Project supported by MOST of China (2008IM020900). National Science Foundation of China (No. 30902003, 30973975, 90709007, and 81072982). China Postdoctoral Science Foundation (No. 20110940553) Publisher Copyright: ©2011 by the Institute of Electrical and Electronics Engineers. All rights reserved

PY - 2011/11/12

Y1 - 2011/11/12

N2 - In the theory of traditional Chinese medicine, deficiency pattern is a distinguished one among patterns in rheumatoid arthritis. As for the explanation of deficiency pattern in rheumatoid arthritis, traditional Chinese medicine explains the deficiency in organs of both liver and kidney. As for the modern medicine, no specific factor available to explain it. In this paper, we propose an approach through data mining to explore the biological basis of deficiency pattern in rheumatoid arthritis. In this approach, the first step is to find the formula in traditional Chinese medicine in the treatment of rheumatoid arthritis. Then, list out the top three diseases which can be regulated by this formula. After that, we can find the networks of biological basis existing among all these three diseases by data mining. By analyzing these networks, directly or not, the deficiency pattern in rheumatoid arthritis might be caused by the chronic inflammation.

AB - In the theory of traditional Chinese medicine, deficiency pattern is a distinguished one among patterns in rheumatoid arthritis. As for the explanation of deficiency pattern in rheumatoid arthritis, traditional Chinese medicine explains the deficiency in organs of both liver and kidney. As for the modern medicine, no specific factor available to explain it. In this paper, we propose an approach through data mining to explore the biological basis of deficiency pattern in rheumatoid arthritis. In this approach, the first step is to find the formula in traditional Chinese medicine in the treatment of rheumatoid arthritis. Then, list out the top three diseases which can be regulated by this formula. After that, we can find the networks of biological basis existing among all these three diseases by data mining. By analyzing these networks, directly or not, the deficiency pattern in rheumatoid arthritis might be caused by the chronic inflammation.

KW - biological basis

KW - chronic inflammation

KW - deficiency pattern

KW - rheumatoid arthritis

KW - text mining

UR - https://www.scopus.com/pages/publications/84856004129

UR - https://ieeexplore.ieee.org/document/6112477

U2 - 10.1109/BIBMW.2011.6112477

DO - 10.1109/BIBMW.2011.6112477

M3 - Conference proceeding

AN - SCOPUS:84856004129

SN - 9781457716126

T3 - IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW

SP - 811

EP - 816

BT - 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011

A2 - Chen, Brian

A2 - Chen, Jake

A2 - Chen, Xin

A2 - Chen, Yidong

A2 - Cho, Young-Rae

A2 - Cui, Juan

A2 - Haspel, Nurit

A2 - He, Jing

A2 - Hsu, Hui-Huang

A2 - Huang, Yufei

A2 - Huang, Kun

A2 - Jiang, Rui

A2 - Khudyakov, Yury

A2 - Kwoh, Chee Keong

A2 - Li, Guojun

A2 - Li, Guo-Zheng

A2 - Mandoiu, Ion

A2 - Park, Taesung

A2 - Policriti, Alberto

A2 - Qin, Zhaohui Steve

A2 - Reddy, Chandan

A2 - Ressom, Habtom

A2 - Satten, Glen

A2 - Schönbach, Christian

A2 - Shehu, Amarda

A2 - Song, Min

A2 - Song, Xiaofeng

A2 - Tseng, Vincent

A2 - Xiong, Zunyan

A2 - Yoo, Illhoi

A2 - Zelikovsky, Alex

A2 - Zhang, Guanglan

A2 - Zhang, Joe

A2 - Zhao, Shaying

A2 - Zhao, Zhongming

A2 - Zheng, Jane

A2 - Zhu, Dongxiao

PB - IEEE

CY - California

T2 - 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops

Y2 - 12 November 2011 through 15 November 2011

ER -

Zheng G, Jiang M, Lu C, Guo H, Zhan J, Lu A. Exploring the biological basis of deficiency pattern in rheumatoid arthritis through text mining. In Chen B, Chen J, Chen X, Chen Y, Cho YR, Cui J, Haspel N, He J, Hsu HH, Huang Y, Huang K, Jiang R, Khudyakov Y, Kwoh CK, Li G, Li GZ, Mandoiu I, Park T, Policriti A, Qin ZS, Reddy C, Ressom H, Satten G, Schönbach C, Shehu A, Song M, Song X, Tseng V, Xiong Z, Yoo I, Zelikovsky A, Zhang G, Zhang J, Zhao S, Zhao Z, Zheng J, Zhu D, editors, 2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2011. California: IEEE. 2011. p. 811-816. (IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW). doi: 10.1109/BIBMW.2011.6112477

Exploring the biological basis of deficiency pattern in rheumatoid arthritis through text mining

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