Exploring the associating rules of prescription and syndrome on Radix Astragali with text mining

Shuyu Sun, Changyuan Yu, Miao Jiang, Minzhi Wang, Xiaojuan He, Aiping LYU, Guang Zheng

Research output: Chapter in book/report/conference proceedingConference contributionpeer-review

Abstract

Single Chinese herbal medicine (CHM) is the basic element in the formulae of traditional Chinese medicine (TCM). How to acquire knowledge of a single CHM within the framework of TCM is a meaningful task. In TCM, Radix Astragali (RA) is frequently and widely used in clinical practice. In order to explore the associating rules between prescription and syndrome on RA with text mining technique, we downloaded the data set on RA from Chinese BioMedical literature database (also called SinoMed). Then, the rules of prescription corresponding to disease and syndrome on RA were mined out by executing data slicing algorithms. The mining results were visually demonstrated with software Cytoscape 2.8. Text mining, together with artificial reading for anti-noising and validation, is an important approach in exploring the rules of prescription corresponding to disease and syndrome. The results showed that RA was usually used in treating diseases of diabetes and cancers. For them, blood stasis due to qi deficiency was the main syndrome in TCM. Moreover, the results demonstrated associations among TCM syndrome, diseases and formulae associated with RA. These associated networks represented a variety of knowledge items which embodied the associating rules between prescription and syndrome on RA.

Original languageEnglish
Title of host publication2013 ICME International Conference on Complex Medical Engineering, CME 2013
Pages115-118
Number of pages4
DOIs
Publication statusPublished - 2013
Event2013 7th ICME International Conference on Complex Medical Engineering, CME 2013 - Beijing, China
Duration: 25 May 201328 May 2013

Publication series

Name2013 ICME International Conference on Complex Medical Engineering, CME 2013

Conference

Conference2013 7th ICME International Conference on Complex Medical Engineering, CME 2013
Country/TerritoryChina
CityBeijing
Period25/05/1328/05/13

Scopus Subject Areas

  • Biomedical Engineering

User-Defined Keywords

  • associating rules
  • Data slicing algorithm
  • Radix Astragali
  • Text mining

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