TY - GEN
T1 - Exploring Li-Fa-Fang-Yao rules of major depressive disorder in traditional Chinese medicine through text mining
AU - Zhan, Junping
AU - Zheng, Guang
AU - Song, Mengmeng
AU - Wei, Tong
AU - Jiang, Miao
AU - Lu, Cheng
AU - LYU, Aiping
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2013
Y1 - 2013
N2 - In traditional Chinese medicine, rules of Li-Fa-Fang-Yao is of critical importance in clinical practices. Li-Fa-Fang-Yao, which means principles, methods, formulae, and Chinese herbal medicines respectively, indicate the four basic steps of diagnosis and treatment: determining the cause, mechanism and location of the disease according to the medical theories and principles, then deciding the treatment principle and method, and finally selecting a formula as well as proper Chinese herbal medicines. In this paper, focused on major depressive disorder, we explored the rules of Li-Fa-Fang-Yao within the framework of traditional Chinese medicine. Through calculation, three clusters of Li-Fa-Fang-Yao on major depressive disorder were found based on the syndrome differentiation. What's more, these three clusters can also be validated by textbooks of traditional Chinese medicine.
AB - In traditional Chinese medicine, rules of Li-Fa-Fang-Yao is of critical importance in clinical practices. Li-Fa-Fang-Yao, which means principles, methods, formulae, and Chinese herbal medicines respectively, indicate the four basic steps of diagnosis and treatment: determining the cause, mechanism and location of the disease according to the medical theories and principles, then deciding the treatment principle and method, and finally selecting a formula as well as proper Chinese herbal medicines. In this paper, focused on major depressive disorder, we explored the rules of Li-Fa-Fang-Yao within the framework of traditional Chinese medicine. Through calculation, three clusters of Li-Fa-Fang-Yao on major depressive disorder were found based on the syndrome differentiation. What's more, these three clusters can also be validated by textbooks of traditional Chinese medicine.
KW - depression
KW - Li-Fa-Fang-Yao
KW - text mining
KW - traditional Chinese medicine
KW - validation
UR - http://www.scopus.com/inward/record.url?scp=84894554291&partnerID=8YFLogxK
U2 - 10.1109/BIBM.2013.6732536
DO - 10.1109/BIBM.2013.6732536
M3 - Conference proceeding
AN - SCOPUS:84894554291
SN - 9781479913091
T3 - Proceedings - 2013 IEEE International Conference on Bioinformatics and Biomedicine, IEEE BIBM 2013
SP - 460
EP - 464
BT - Proceedings - 2013 IEEE International Conference on Bioinformatics and Biomedicine, IEEE BIBM 2013
T2 - 2013 IEEE International Conference on Bioinformatics and Biomedicine, IEEE BIBM 2013
Y2 - 18 December 2013 through 21 December 2013
ER -