Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells

David G. Smith; Ga Lai Law; Benjamin S. Murray; Robert Pal; David Parker; Ka Leung Wong

doi:10.1039/c1cc11853f

Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells

David G. Smith, Ga Lai Law, Benjamin S. Murray, Robert Pal, David Parker^*, Ka Leung Wong

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

44 Citations (Scopus)

Abstract

Image and spectral intensity from bicarbonate-selective europium(iii) probes localised in the mitochondria of cells is modulated reversibly by variation of external pCO₂, and is suppressed by addition of the carbonic anhydrase inhibitor, acetazolomide.

Original language	English
Pages (from-to)	7347-7349
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	26
DOIs	https://doi.org/10.1039/c1cc11853f
Publication status	Published - 14 Jul 2011

Scopus Subject Areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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title = "Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells",

abstract = "Image and spectral intensity from bicarbonate-selective europium(iii) probes localised in the mitochondria of cells is modulated reversibly by variation of external pCO2, and is suppressed by addition of the carbonic anhydrase inhibitor, acetazolomide.",

author = "Smith, {David G.} and Law, {Ga Lai} and Murray, {Benjamin S.} and Robert Pal and David Parker and Wong, {Ka Leung}",

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AU - Smith, David G.

AU - Law, Ga Lai

AU - Murray, Benjamin S.

AU - Pal, Robert

AU - Parker, David

AU - Wong, Ka Leung

PY - 2011/7/14

Y1 - 2011/7/14

N2 - Image and spectral intensity from bicarbonate-selective europium(iii) probes localised in the mitochondria of cells is modulated reversibly by variation of external pCO2, and is suppressed by addition of the carbonic anhydrase inhibitor, acetazolomide.

AB - Image and spectral intensity from bicarbonate-selective europium(iii) probes localised in the mitochondria of cells is modulated reversibly by variation of external pCO2, and is suppressed by addition of the carbonic anhydrase inhibitor, acetazolomide.

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U2 - 10.1039/c1cc11853f

DO - 10.1039/c1cc11853f

M3 - Journal article

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SP - 7347

EP - 7349

JO - Chemical Communications

JF - Chemical Communications

IS - 26

ER -

Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells

Abstract

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