EuroTracker dyes: Highly emissive europium complexes as alternative organelle stains for live cell imaging

  • Stephen J. Butler
  • , Laurent Lamarque
  • , Robert Pal
  • , David Parker*
  • *Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

134 Citations (Scopus)

Abstract

Nine very bright europium(iii) complexes with different macrocyclic ligands have been prepared that exhibit excellent cell uptake behaviour and distinctive sub-cellular localisation profiles, allowing the use of fluorescence microscopy and time-gated spectral imaging to track their fate in cellulo . Their use as cellular imaging stains is described for the selective illumination of mitochondria, lysosomes or the endoplasmic reticulum of various mammalian cell types.

Original languageEnglish
Pages (from-to)1750-1756
Number of pages7
JournalChemical Science
Volume5
Issue number5
Early online date27 Jan 2014
DOIs
Publication statusPublished - 1 Apr 2014

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