EuroTracker dyes: Highly emissive europium complexes as alternative organelle stains for live cell imaging

Stephen J. Butler; Laurent Lamarque; Robert Pal; David Parker

doi:10.1039/c3sc53056f

EuroTracker dyes: Highly emissive europium complexes as alternative organelle stains for live cell imaging

Stephen J. Butler
, Laurent Lamarque
, Robert Pal
, David Parker^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

136 Citations (Scopus)

Abstract

Nine very bright europium(iii) complexes with different macrocyclic ligands have been prepared that exhibit excellent cell uptake behaviour and distinctive sub-cellular localisation profiles, allowing the use of fluorescence microscopy and time-gated spectral imaging to track their fate in cellulo . Their use as cellular imaging stains is described for the selective illumination of mitochondria, lysosomes or the endoplasmic reticulum of various mammalian cell types.

Original language	English
Pages (from-to)	1750-1756
Number of pages	7
Journal	Chemical Science
Volume	5
Issue number	5
Early online date	27 Jan 2014
DOIs	https://doi.org/10.1039/c3sc53056f
Publication status	Published - 1 Apr 2014

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title = "EuroTracker dyes: Highly emissive europium complexes as alternative organelle stains for live cell imaging",

abstract = "Nine very bright europium(iii) complexes with different macrocyclic ligands have been prepared that exhibit excellent cell uptake behaviour and distinctive sub-cellular localisation profiles, allowing the use of fluorescence microscopy and time-gated spectral imaging to track their fate in cellulo . Their use as cellular imaging stains is described for the selective illumination of mitochondria, lysosomes or the endoplasmic reticulum of various mammalian cell types.",

author = "Butler, \{Stephen J.\} and Laurent Lamarque and Robert Pal and David Parker",

note = "We thank the ERC for support (DP, SJB, RP; FCC 266804). Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2014",

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T1 - EuroTracker dyes

T2 - Highly emissive europium complexes as alternative organelle stains for live cell imaging

AU - Butler, Stephen J.

AU - Lamarque, Laurent

AU - Pal, Robert

AU - Parker, David

PY - 2014/4/1

Y1 - 2014/4/1

N2 - Nine very bright europium(iii) complexes with different macrocyclic ligands have been prepared that exhibit excellent cell uptake behaviour and distinctive sub-cellular localisation profiles, allowing the use of fluorescence microscopy and time-gated spectral imaging to track their fate in cellulo . Their use as cellular imaging stains is described for the selective illumination of mitochondria, lysosomes or the endoplasmic reticulum of various mammalian cell types.

AB - Nine very bright europium(iii) complexes with different macrocyclic ligands have been prepared that exhibit excellent cell uptake behaviour and distinctive sub-cellular localisation profiles, allowing the use of fluorescence microscopy and time-gated spectral imaging to track their fate in cellulo . Their use as cellular imaging stains is described for the selective illumination of mitochondria, lysosomes or the endoplasmic reticulum of various mammalian cell types.

UR - https://www.scopus.com/pages/publications/84898079580

U2 - 10.1039/c3sc53056f

DO - 10.1039/c3sc53056f

M3 - Journal article

AN - SCOPUS:84898079580

SN - 2041-6520

VL - 5

SP - 1750

EP - 1756

JO - Chemical Science

JF - Chemical Science

IS - 5

ER -

EuroTracker dyes: Highly emissive europium complexes as alternative organelle stains for live cell imaging

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