Abstract
A mark variable is a generalization of measurements such as lifetime medical costs and quality-adjusted lifetimes. Recently, analysis of the mark variable has generated significant interest as an important component in health treatment evaluation. In this paper, a novel approach to estimating the mean of the mark variable under right censoring is proposed. The proposed estimator is of a much simpler form than most existing estimators advocated in the literature. Theoretical analysis and simulation studies indicate that the proposed estimator has practical applications due to its simplicity and accuracy. A real data set, from a Multicenter Automatic Defibrillator Implantation Trial (MADIT), is used to illustrate the proposed methodology.
| Original language | English |
|---|---|
| Pages (from-to) | 1726-1735 |
| Number of pages | 10 |
| Journal | Computational Statistics and Data Analysis |
| Volume | 55 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1 Apr 2011 |
User-Defined Keywords
- KaplanMeier estimator
- Lifetime medical cost
- Mark variable
- Martingale
- Quality-adjusted lifetime
- Survival analysis
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