Abstract
Silicon quantum dots have become one of the most popular nanomaterials in biological applications for their excellent biocompatibility and optical properties. Herein, we synthesized amino-functionalized silicon quantum dots (NH 2 @SiQDs) via a simple microemulsion method, in which silicon tetrachloride and allylamine were used as source of silicon and functional group. NH 2 @SiQDs exhibits good water-solubility, high fluorescence quantum yield and optical stability. A non-enzymatic biosensor of glucose was developed based on the fluorescence quenching of NH 2 @SiQDs in response to glucose. The fluorescence response was linearly proportional to glucose in the concentration range of 1.0 × 10 −6 –9.0 × 10 −5 mol/L and the detection limit was determined to be 3.0 × 10 −7 mol/L. The developed glucose sensor was successfully applied in blood glucose analysis of human serum. Satisfactory result that agreed very well with traditional method was obtained.
Original language | English |
---|---|
Pages (from-to) | 303-309 |
Number of pages | 7 |
Journal | Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy |
Volume | 216 |
DOIs | |
Publication status | Published - 5 Jun 2019 |
User-Defined Keywords
- A glucose sensor
- Enzyme free
- Fluorescence quenching
- Silicon quantum dots