ent-Kaurene diterpenoids from Isodon oresbius

Wei Xiang, Rong Tao Li, Zong Yu Wang, Sheng Hong Li, Qin Shi Zhao, Hong Jie Zhang, Han Dong Sun*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

24 Citations (Scopus)


Three new ent-kaurene diterpenoids, oreskaurins A-C (1-3), together with ten known ent-kaurene diterpenoids, enmenin monoacetate (4), effusanin E (5), adenolin B (6), maoecrystal G (7), enmelol (8), trichokaurin (9), sodoponin (10), trichorabdal A (11), nodosin (12), enmein (13), and a flavonoid, vitexin (14), were isolated from Isodon oresbius. Their structures were determined by spectroscopic means. Compound 12 showed inhibitory activity toward K562 cells with IC50=1.43 μg/ml.

Three new ent-kaurene diterpenoids, oreskaurins A–C (1–3), and eleven known compounds were isolated from Isodon oresbius.

Original languageEnglish
Pages (from-to)1173-1177
Number of pages5
Issue number8
Publication statusPublished - Apr 2004

Scopus Subject Areas

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture

User-Defined Keywords

  • Cytotoxicity
  • ent-Kaurenoid
  • Isodon oresbius
  • Labiatae
  • Oreskaurins A-C


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