ent-Kaurene Diterpenoids from Isodon adenanthus

Wei Xiang, Quan-Bin Han, Sheng-Hong Li, Zhi Na, Han-Dong Sun*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

6 Citations (Scopus)


Three new ent-kaurene diterpenoids, adenanthins N, O and P (1-3), and four known diterpenoids, leucophyllin E (4), glabcensin C (5), adenanthin A (6), leucophyllin 8 (7), together with a highly unsaturated fatty acid, 9,16-dioxo-10,12,14-octadeca-trienoic acid (8), were isolated from Isodon adenanthus (Diels) Kudo. The structure of compound 4 was revised accordingly. Compound 1 showed significant cytotoxic activity against K562 cells with IC50 = 0.45 μg/mL.
Original languageEnglish
Pages (from-to)1383-1386
Number of pages4
JournalJournal of Integrative Plant Biology
Issue number11
Publication statusPublished - Nov 2003

User-Defined Keywords

  • Isodon adenanthus
  • Labiatae
  • ent-kauranoids
  • adenanthins N, O and P


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