Abstract
Three new ent-kaurene diterpenoids, adenanthins N, O and P (1-3), and four known diterpenoids, leucophyllin E (4), glabcensin C (5), adenanthin A (6), leucophyllin 8 (7), together with a highly unsaturated fatty acid, 9,16-dioxo-10,12,14-octadeca-trienoic acid (8), were isolated from Isodon adenanthus (Diels) Kudo. The structure of compound 4 was revised accordingly. Compound 1 showed significant cytotoxic activity against K562 cells with IC50 = 0.45 μg/mL.
| Original language | English |
|---|---|
| Pages (from-to) | 1383-1386 |
| Number of pages | 4 |
| Journal | Journal of Integrative Plant Biology |
| Volume | 45 |
| Issue number | 11 |
| Publication status | Published - Nov 2003 |
User-Defined Keywords
- Isodon adenanthus
- Labiatae
- ent-kauranoids
- adenanthins N, O and P