TY - JOUR
T1 - Ent-kauranoids from Isodon rubescens var. taihangensis
AU - Han, Quan Bin
AU - Li, Rong Tao
AU - Li, Ma Lin
AU - Mou, Yi Kun
AU - Tian, Qing E.
AU - Li, Si Wei
AU - Sun, Han Dong
PY - 2005/2
Y1 - 2005/2
N2 - Two new compounds, rubescensins Q and R, and a new acetonide derivative of lasiodonin, together with thirteen known analogues, oridonin, ponicidin, wikstroemioidin B, lasiodonin, lasiokaurin, enmenol, 1-O-β-D- glucopyranosyl-enmenol, trichokaurin, the acetonide of maoyecrystal F, rabdoternins A-D, have been isolated from Isodon rubescens var. taihangensis. The structures of the new compounds were elucidated on the basis of spectroscopic methods, especially the 2D NMR spectral analysis. Compound 3 exhibited cytotoxicity against K562, Bcap37, CA, CNE, BIU87, BGC823, and HeLa cell lines.
AB - Two new compounds, rubescensins Q and R, and a new acetonide derivative of lasiodonin, together with thirteen known analogues, oridonin, ponicidin, wikstroemioidin B, lasiodonin, lasiokaurin, enmenol, 1-O-β-D- glucopyranosyl-enmenol, trichokaurin, the acetonide of maoyecrystal F, rabdoternins A-D, have been isolated from Isodon rubescens var. taihangensis. The structures of the new compounds were elucidated on the basis of spectroscopic methods, especially the 2D NMR spectral analysis. Compound 3 exhibited cytotoxicity against K562, Bcap37, CA, CNE, BIU87, BGC823, and HeLa cell lines.
KW - Cytotoxic activity
KW - ent-Kaurene diterpenoid
KW - Isodon rubescens var. taihangensis
KW - Labiatae
KW - Rubescensins Q and R
UR - https://www.ingentaconnect.com/content/tandf/ganp/2005/00000007/00000001/art00006
UR - https://www.scopus.com/pages/publications/11844265901
U2 - 10.1080/10286020310001608985
DO - 10.1080/10286020310001608985
M3 - Journal article
SN - 1028-6020
VL - 7
SP - 31
EP - 36
JO - Journal of Asian Natural Products Research
JF - Journal of Asian Natural Products Research
IS - 1
ER -