Ent-kauranoids from Isodon rubescens var. taihangensis

Quan Bin Han, Rong Tao Li, Ma Lin Li, Yi Kun Mou, Qing E. Tian, Si Wei Li, Han Dong Sun*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

20 Citations (Scopus)


Two new compounds, rubescensins Q and R, and a new acetonide derivative of lasiodonin, together with thirteen known analogues, oridonin, ponicidin, wikstroemioidin B, lasiodonin, lasiokaurin, enmenol, 1-O-β-D- glucopyranosyl-enmenol, trichokaurin, the acetonide of maoyecrystal F, rabdoternins A-D, have been isolated from Isodon rubescens var. taihangensis. The structures of the new compounds were elucidated on the basis of spectroscopic methods, especially the 2D NMR spectral analysis. Compound 3 exhibited cytotoxicity against K562, Bcap37, CA, CNE, BIU87, BGC823, and HeLa cell lines.

Original languageEnglish
Pages (from-to)31-36
Number of pages6
JournalJournal of Asian Natural Products Research
Issue number1
Publication statusPublished - Feb 2005

Scopus Subject Areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

User-Defined Keywords

  • Cytotoxic activity
  • ent-Kaurene diterpenoid
  • Isodon rubescens var. taihangensis
  • Labiatae
  • Rubescensins Q and R


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