Ent-kauranoids from Isodon rubescens var. taihangensis

Quan Bin Han; Rong Tao Li; Ma Lin Li; Yi Kun Mou; Qing E. Tian; Si Wei Li; Han Dong Sun

doi:10.1080/10286020310001608985

Ent-kauranoids from Isodon rubescens var. taihangensis

Quan Bin Han, Rong Tao Li, Ma Lin Li, Yi Kun Mou, Qing E. Tian, Si Wei Li, Han Dong Sun^*

^*Corresponding author for this work

Chinese Medicine - Teaching and Research Division

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

Two new compounds, rubescensins Q and R, and a new acetonide derivative of lasiodonin, together with thirteen known analogues, oridonin, ponicidin, wikstroemioidin B, lasiodonin, lasiokaurin, enmenol, 1-O-β-D- glucopyranosyl-enmenol, trichokaurin, the acetonide of maoyecrystal F, rabdoternins A-D, have been isolated from Isodon rubescens var. taihangensis. The structures of the new compounds were elucidated on the basis of spectroscopic methods, especially the 2D NMR spectral analysis. Compound 3 exhibited cytotoxicity against K562, Bcap37, CA, CNE, BIU87, BGC823, and HeLa cell lines.

Original language	English
Pages (from-to)	31-36
Number of pages	6
Journal	Journal of Asian Natural Products Research
Volume	7
Issue number	1
DOIs	https://doi.org/10.1080/10286020310001608985
Publication status	Published - Feb 2005

Scopus Subject Areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

User-Defined Keywords

Cytotoxic activity
ent-Kaurene diterpenoid
Isodon rubescens var. taihangensis
Labiatae
Rubescensins Q and R

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10.1080/10286020310001608985

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title = "Ent-kauranoids from Isodon rubescens var. taihangensis",

abstract = "Two new compounds, rubescensins Q and R, and a new acetonide derivative of lasiodonin, together with thirteen known analogues, oridonin, ponicidin, wikstroemioidin B, lasiodonin, lasiokaurin, enmenol, 1-O-β-D- glucopyranosyl-enmenol, trichokaurin, the acetonide of maoyecrystal F, rabdoternins A-D, have been isolated from Isodon rubescens var. taihangensis. The structures of the new compounds were elucidated on the basis of spectroscopic methods, especially the 2D NMR spectral analysis. Compound 3 exhibited cytotoxicity against K562, Bcap37, CA, CNE, BIU87, BGC823, and HeLa cell lines.",

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author = "Han, {Quan Bin} and Li, {Rong Tao} and Li, {Ma Lin} and Mou, {Yi Kun} and Tian, {Qing E.} and Li, {Si Wei} and Sun, {Han Dong}",

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T1 - Ent-kauranoids from Isodon rubescens var. taihangensis

AU - Han, Quan Bin

AU - Li, Rong Tao

AU - Li, Ma Lin

AU - Mou, Yi Kun

AU - Tian, Qing E.

AU - Li, Si Wei

AU - Sun, Han Dong

PY - 2005/2

Y1 - 2005/2

N2 - Two new compounds, rubescensins Q and R, and a new acetonide derivative of lasiodonin, together with thirteen known analogues, oridonin, ponicidin, wikstroemioidin B, lasiodonin, lasiokaurin, enmenol, 1-O-β-D- glucopyranosyl-enmenol, trichokaurin, the acetonide of maoyecrystal F, rabdoternins A-D, have been isolated from Isodon rubescens var. taihangensis. The structures of the new compounds were elucidated on the basis of spectroscopic methods, especially the 2D NMR spectral analysis. Compound 3 exhibited cytotoxicity against K562, Bcap37, CA, CNE, BIU87, BGC823, and HeLa cell lines.

AB - Two new compounds, rubescensins Q and R, and a new acetonide derivative of lasiodonin, together with thirteen known analogues, oridonin, ponicidin, wikstroemioidin B, lasiodonin, lasiokaurin, enmenol, 1-O-β-D- glucopyranosyl-enmenol, trichokaurin, the acetonide of maoyecrystal F, rabdoternins A-D, have been isolated from Isodon rubescens var. taihangensis. The structures of the new compounds were elucidated on the basis of spectroscopic methods, especially the 2D NMR spectral analysis. Compound 3 exhibited cytotoxicity against K562, Bcap37, CA, CNE, BIU87, BGC823, and HeLa cell lines.

KW - Cytotoxic activity

KW - ent-Kaurene diterpenoid

KW - Isodon rubescens var. taihangensis

KW - Labiatae

KW - Rubescensins Q and R

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JO - Journal of Asian Natural Products Research

JF - Journal of Asian Natural Products Research

IS - 1

ER -

Ent-kauranoids from Isodon rubescens var. taihangensis

Abstract

Scopus Subject Areas

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