Abstract
Nine new ent-kaurane diterpenoids, isoscoparins D-L (1-9), and an artificial product, the acetonide of rabdoloxin A (10), along with 16 known analogues (11-26), were isolated from the leaves of Isodon scoparius. The new structures were determined by 1D and 2D NMR spectroscopic analysis. Selected compounds were evaluated for their cytotoxicity against NB4, A549, PC-3, MCF-7, and SH-SY5Y cell lines.
Original language | English |
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Pages (from-to) | 125-129 |
Number of pages | 5 |
Journal | Journal of Natural Products |
Volume | 72 |
Issue number | 1 |
Early online date | 11 Dec 2008 |
DOIs | |
Publication status | Published - 23 Jan 2009 |
Scopus Subject Areas
- Analytical Chemistry
- Molecular Medicine
- Pharmacology
- Pharmaceutical Science
- Drug Discovery
- Complementary and alternative medicine
- Organic Chemistry