Abstract
Three new 6,7-seco-6,19:6,20-diepoxy-1α,7-olide-ent-kaurane diterpenoids, ludongnins C-E (1-3), along with six known analogs, macrocalyxoformins A (4) and B (5), sculponeatins A (6) and B (7), and ludongnins A (8) and B (9), were isolated from Isodon rubescens var. lushiensis. The structures of the new compounds were determined on the basis of the spectroscopic evidences. Compound (5) exhibited significant inhibitory activities against the Bcap37 and K562 cell lines with IC50 = 0.82 and 0.62 μg/mL, respectively.
Original language | English |
---|---|
Pages (from-to) | 933-938 |
Number of pages | 6 |
Journal | Heterocycles |
Volume | 60 |
Issue number | 4 |
Early online date | 4 Feb 2003 |
DOIs | |
Publication status | Published - 1 Apr 2003 |
Scopus Subject Areas
- Analytical Chemistry
- Pharmacology
- Organic Chemistry