Abstract
ent-Abietane diterpenoids, hebeiabinins A-F (1-5), together with seven known diterpenoids were isolated from leaves of Isodon rubescens var. rubescens. The structures of 1-5 were established on the basis of spectroscopic analyses, including application of 2D NMR spectroscopic techniques. The diterpenoids isolated were evaluated for the cytotoxicity against A549, HT-29, and K562 tumor cells. Compound 5 was the most active with IC50 value of 0.91 μM against A549 cells.
Original language | English |
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Pages (from-to) | 616-622 |
Number of pages | 7 |
Journal | Phytochemistry |
Volume | 68 |
Issue number | 5 |
DOIs | |
Publication status | Published - Mar 2007 |
Scopus Subject Areas
- Biochemistry
- Molecular Biology
- Plant Science
- Horticulture
User-Defined Keywords
- Cytotoxicity
- Diterpenoid
- ent-Abietane
- Hebeiabinin
- Isodon rubescens var. rubescens
- Labiatae