ent-Abietane diterpenoids, hebeiabinins A-F (1-5), together with seven known diterpenoids were isolated from leaves of Isodon rubescens var. rubescens. The structures of 1-5 were established on the basis of spectroscopic analyses, including application of 2D NMR spectroscopic techniques. The diterpenoids isolated were evaluated for the cytotoxicity against A549, HT-29, and K562 tumor cells. Compound 5 was the most active with IC50 value of 0.91 μM against A549 cells.
|Number of pages||7|
|Publication status||Published - Mar 2007|
Scopus Subject Areas
- Molecular Biology
- Plant Science
- Isodon rubescens var. rubescens