End-point sampling

Yuan YAO, Wen Yu, Kani Chen

Research output: Contribution to journalJournal articlepeer-review

4 Citations (Scopus)


Retrospective sampling designs, including case-cohort and case-control designs, are commonly used for failure time data in the presence of censoring. In this paper, we propose a new retrospective sampling design, called end-point sampling, which improves the efficiency of the case-cohort and case-control designs. The regression analysis is conducted using the Cox model. Under different assumptions, the maximum likelihood approach with computational aid from the EM algorithm, and the inverse probability weighting approach are developed respectively to estimate the regression parameters. The resulting estimators are shown to be consistent and asymptotically normal. Simulation and a real data study show favorable evidence for the proposed design in comparison with existing ones.

Original languageEnglish
Pages (from-to)415-435
Number of pages21
JournalStatistica Sinica
Issue number1
Publication statusPublished - Jan 2017

Scopus Subject Areas

  • Statistics and Probability
  • Statistics, Probability and Uncertainty

User-Defined Keywords

  • Case-control sampling
  • Cox model
  • EM algorithm
  • Inverse probability weighting
  • Maximum likelihood estimation
  • Retrospective sampling


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