Abstract
An enantioselective hydrophosphination of alkenyl isoquinolines is developed by using a copper-chiral diphosphine ligand catalyst. It provides a direct and atom-efficient approach to prepare a variety of chiral phosphines with an isoquinoline unit in good yields and high enantioselectivities. In addition, these chiral phosphine products are useful bidentate P,N-ligands which showed potential application in asymmetric catalysis.
Original language | English |
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Pages (from-to) | 4413-4417 |
Number of pages | 5 |
Journal | Chemical Science |
Volume | 14 |
Issue number | 16 |
Early online date | 21 Mar 2023 |
DOIs | |
Publication status | Published - 28 Apr 2023 |
Scopus Subject Areas
- General Chemistry