Emerging trends in the pretreatment of microalgal biomass and recovery of value-added products: A review

Nirakar Pradhan, Sanjay Kumar, Rangabhashiyam Selvasembian, Shweta Rawat, Agendra Gangwar, R Senthamizh, Yuk Kit Yuen, Lijun Luo, Seenivasan Ayothiraman, Ganesh Dattatraya Saratale, Joyabrata Mal*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

15 Citations (Scopus)


Microalgae are a promising source of raw material (i.e., proteins, carbohydrates, lipids, pigments, and micronutrients) for various value-added products and act as a carbon sink for atmospheric CO2. The rigidity of the microalgal cell wall makes it difficult to extract different cellular components for its applications, including biofuel production, food and feed supplements, and pharmaceuticals. To improve the recovery of products from microalgae, pretreatment strategies such as biological, physical, chemical, and combined methods have been explored to improve whole-cell disruption and product recovery efficiency. However, the diversity and uniqueness of the microalgal cell wall make the pretreatment process more species-specific and limit its large-scale application. Therefore, advancing the currently available technologies is required from an economic, technological, and environmental perspective. Thus, this paper provides a state-of-art review of the current trends, challenges, and prospects of sustainable microalgal pretreatment technologies from a microalgae-based biorefinery concept.
Original languageEnglish
Article number128395
Number of pages12
JournalBioresource Technology
Publication statusPublished - Feb 2023

Scopus Subject Areas

  • Bioengineering
  • Waste Management and Disposal
  • Environmental Engineering
  • Renewable Energy, Sustainability and the Environment

User-Defined Keywords

  • Biorefinery
  • Microalgae
  • Pretreatment
  • Value-added products
  • Wastewater


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