Efficient relaxivity enhancement in dendritic gadolinium complexes: Effective motional coupling in medium molecular weight conjugates

David A. Fulton; Mark O'Halloran; David Parker; Kanthi Senanayake; Mauro Botta; Silvio Aime

doi:10.1039/b413536a

Efficient relaxivity enhancement in dendritic gadolinium complexes: Effective motional coupling in medium molecular weight conjugates

David A. Fulton
, Mark O'Halloran
, David Parker^*
, Kanthi Senanayake
, Mauro Botta
, Silvio Aime

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

59 Citations (Scopus)

Abstract

Enhancement of the relaxivities of Gd-based MRI contrast agents is achieved by placing the metal ion at the barycentre of the molecular complex in order to improve motional coupling.

Original language	English
Pages (from-to)	474-476
Number of pages	3
Journal	Chemical Communications
Issue number	4
Early online date	17 Dec 2004
DOIs	https://doi.org/10.1039/b413536a
Publication status	Published - 28 Jan 2005

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@article{a6ced82085294b489f4b6026bfde0e33,

title = "Efficient relaxivity enhancement in dendritic gadolinium complexes: Effective motional coupling in medium molecular weight conjugates",

abstract = "Enhancement of the relaxivities of Gd-based MRI contrast agents is achieved by placing the metal ion at the barycentre of the molecular complex in order to improve motional coupling.",

author = "Fulton, \{David A.\} and Mark O'Halloran and David Parker and Kanthi Senanayake and Mauro Botta and Silvio Aime",

note = "We thank EPSRC (DF, KS), the EPSRC-National MS Service for assistance and ESF-COST-Action-D-18 for support. Publisher copyright: {\textcopyright} Royal Society of Chemistry 2005",

year = "2005",

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doi = "10.1039/b413536a",

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T1 - Efficient relaxivity enhancement in dendritic gadolinium complexes

T2 - Effective motional coupling in medium molecular weight conjugates

AU - Fulton, David A.

AU - O'Halloran, Mark

AU - Parker, David

AU - Senanayake, Kanthi

AU - Botta, Mauro

AU - Aime, Silvio

PY - 2005/1/28

Y1 - 2005/1/28

N2 - Enhancement of the relaxivities of Gd-based MRI contrast agents is achieved by placing the metal ion at the barycentre of the molecular complex in order to improve motional coupling.

AB - Enhancement of the relaxivities of Gd-based MRI contrast agents is achieved by placing the metal ion at the barycentre of the molecular complex in order to improve motional coupling.

UR - https://www.scopus.com/pages/publications/13244258348

U2 - 10.1039/b413536a

DO - 10.1039/b413536a

M3 - Journal article

C2 - 15654374

AN - SCOPUS:13244258348

SN - 1359-7345

SP - 474

EP - 476

JO - Chemical Communications

JF - Chemical Communications

IS - 4

ER -

Efficient relaxivity enhancement in dendritic gadolinium complexes: Effective motional coupling in medium molecular weight conjugates

Abstract

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