Effects of chronic tramadol exposure on the zebrafish brain: A proteomic study

Keyphrases

• Proteomic Study 100%
• Zebrafish Brain 100%
• Tramadol Hydrochloride 100%
• Tramadol 100%
• ATP Synthase 50%
• Tubulin 50%
• 14-3-3 Protein 50%
• Creatine Kinase 50%
• N-desmethyltramadol 50%
• Weight Loss 25%
• Differentially Expressed Proteins 25%
• Mitochondria 25%
• Oxidative Stress 25%
• Morphological Changes 25%
• Neurotoxicity 25%
• Protein Spots 25%
• Proteomic Analysis 25%
• Responsive Proteins 25%
• Apoptosis 25%
• Abnormal Behavior 25%
• Actin 25%
• Energy Metabolism 25%
• Brain Tissue 25%
• Associated Proteins 25%
• Oxidative Damage 25%
• Ubiquitin 25%
• Hydrolases 25%
• Beta Chain 25%
• Abuse Potential 25%
• Prescribed Opioids 25%
• O-desmethyltramadol 25%
• Ultrastructural Observation 25%
• Disordered Structure 25%
• 2D-PAGE 25%
• Cytoskeletal Structure 25%
• Page Analysis 25%
• Synaptosomes 25%
• Irregular Bodies 25%
• Carboxyl Terminus 25%
• Mitochondrium 25%

Neuroscience

• Proteomics 100%
• Tramadol 100%
• 14-3-3 Protein 40%
• ATP Synthase 40%
• Programmed Cell Death 20%
• Neurotoxicity 20%
• Mitochondrion 20%
• Oxidative Stress 20%
• Polyacrylamide Gel Electrophoresis 20%
• Ubiquitin Thiolesterase 20%
• Synaptosome 20%
• Creatine Kinase 20%
• Beta Chain 20%
• Actin 20%
• Energy Metabolism 20%
• Creatine Kinase BB 20%
• Tubulin 20%
• Beta Tubulin 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Zebra fish 100%
• Tramadol 100%
• Adenosine Triphosphate 40%
• Tubulin 40%
• Synthetase 40%
• Protein 14 3 3 40%
• Neurotoxicity 20%
• Actin 20%
• Polyacrylamide Gel Electrophoresis 20%
• Ubiquitin Thiolesterase 20%
• Creatine Kinase BB 20%
• Creatine Kinase 20%