Effects of ambient air pollution on lung function growth in Chinese schoolchildren

Qi Qiang He; Tze Wai Wong; Lin Du; Zhuo Qin Jiang; Yang Gao; Hong Qiu; Wei Jia Liu; Jia Gang Wu; Andromeda Wong; Tak Sun Ignatius Yu

doi:10.1016/j.rmed.2010.04.016

Effects of ambient air pollution on lung function growth in Chinese schoolchildren

Qi Qiang He
, Tze Wai Wong^*
, Lin Du
, Zhuo Qin Jiang
, Yang Gao
, Hong Qiu
, Wei Jia Liu
, Jia Gang Wu
, Andromeda Wong
, Tak Sun Ignatius Yu

^*Corresponding author for this work

Academy of Wellness and Human Development

Research output: Contribution to journal › Journal article › peer-review

58 Citations (Scopus)

Abstract

Objective: To evaluate the adverse effect of exposure to air pollution on lung function growth in school-aged children.

Methods: A cohort of 1983 children from three districts in Guangzhou, China was followed-up for 6 months. The children performed pulmonary function tests twice, and their parents reported the child's respiratory symptoms by self-administered questionnaires in both surveys.

Results: The annual mean concentrations of air pollutants for the past 5 years for particulate matter less than 10 microns in diameter (PM ₁₀), nitrogen (NO₂), and sulfur dioxide (SO₂) were respectively: 96.1 μg/m³, 76.0 μg/m³, and 65.7 μg/m³ in the highly-polluted district (HPD), 80.3 μg/m ³, 67.6 μg/m³, and 54.5 μg/m³ in the moderately-polluted district (MPD), and 80.0 μg/m³, 48.1 μg/m³, and 52.2 μg/m³ in the least-polluted district (LPD). After adjustment for potential confounders, significant deficits were found in the annual growth rates of forced expiratory flows at 25% (FEF ₂₅), and between 25% and 75% (FEF_25-75) in boys and FEF₂₅ in girls (In boys, for FEF₂₅, -0.136 l/s, p = 0.008 in MPD and -0.153 l/s, p = 0.004 in HPD, respectively; for FEF_25-75, -0.176 l/s, p = 0.013 in MPD and -0.167 l/s, p = 0.021 in HPD, respectively. In girls, for FEF₂₅, -0.123 l/s, p = 0.043 in HPD), using LPD as the reference. Deficits in the annual growth rate of forced expiratory volume in 1 s (FEV₁) were also negatively associated with air pollution in boys (-0.063 L, p = 0.032 in HPD).

Conclusions: The study adds more evidence that exposure to air pollution has adverse effects on lung function growth in schoolchildren.

Original language	English
Pages (from-to)	1512-1520
Number of pages	9
Journal	Respiratory Medicine
Volume	104
Issue number	10
Early online date	14 May 2010
DOIs	https://doi.org/10.1016/j.rmed.2010.04.016
Publication status	Published - Oct 2010

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

User-Defined Keywords

Air pollution
Children
Cohort study
Lung function growth

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10.1016/j.rmed.2010.04.016

Cite this

@article{af072d21658248559ef88fe2c39d4acc,

title = "Effects of ambient air pollution on lung function growth in Chinese schoolchildren",

abstract = "Objective: To evaluate the adverse effect of exposure to air pollution on lung function growth in school-aged children. Methods: A cohort of 1983 children from three districts in Guangzhou, China was followed-up for 6 months. The children performed pulmonary function tests twice, and their parents reported the child's respiratory symptoms by self-administered questionnaires in both surveys.Results: The annual mean concentrations of air pollutants for the past 5 years for particulate matter less than 10 microns in diameter (PM 10), nitrogen (NO2), and sulfur dioxide (SO2) were respectively: 96.1 μg/m3, 76.0 μg/m3, and 65.7 μg/m3 in the highly-polluted district (HPD), 80.3 μg/m 3, 67.6 μg/m3, and 54.5 μg/m3 in the moderately-polluted district (MPD), and 80.0 μg/m3, 48.1 μg/m3, and 52.2 μg/m3 in the least-polluted district (LPD). After adjustment for potential confounders, significant deficits were found in the annual growth rates of forced expiratory flows at 25\% (FEF 25), and between 25\% and 75\% (FEF25-75) in boys and FEF25 in girls (In boys, for FEF25, -0.136 l/s, p = 0.008 in MPD and -0.153 l/s, p = 0.004 in HPD, respectively; for FEF25-75, -0.176 l/s, p = 0.013 in MPD and -0.167 l/s, p = 0.021 in HPD, respectively. In girls, for FEF25, -0.123 l/s, p = 0.043 in HPD), using LPD as the reference. Deficits in the annual growth rate of forced expiratory volume in 1 s (FEV1) were also negatively associated with air pollution in boys (-0.063 L, p = 0.032 in HPD).Conclusions: The study adds more evidence that exposure to air pollution has adverse effects on lung function growth in schoolchildren.",

keywords = "Air pollution, Children, Cohort study, Lung function growth",

author = "He, \{Qi Qiang\} and Wong, \{Tze Wai\} and Lin Du and Jiang, \{Zhuo Qin\} and Yang Gao and Hong Qiu and Liu, \{Wei Jia\} and Wu, \{Jia Gang\} and Andromeda Wong and Yu, \{Tak Sun Ignatius\}",

year = "2010",

month = oct,

doi = "10.1016/j.rmed.2010.04.016",

language = "English",

volume = "104",

pages = "1512--1520",

journal = "Respiratory Medicine",

issn = "0954-6111",

publisher = "W.B. Saunders Ltd",

number = "10",

}

TY - JOUR

T1 - Effects of ambient air pollution on lung function growth in Chinese schoolchildren

AU - He, Qi Qiang

AU - Wong, Tze Wai

AU - Du, Lin

AU - Jiang, Zhuo Qin

AU - Gao, Yang

AU - Qiu, Hong

AU - Liu, Wei Jia

AU - Wu, Jia Gang

AU - Wong, Andromeda

AU - Yu, Tak Sun Ignatius

PY - 2010/10

Y1 - 2010/10

N2 - Objective: To evaluate the adverse effect of exposure to air pollution on lung function growth in school-aged children. Methods: A cohort of 1983 children from three districts in Guangzhou, China was followed-up for 6 months. The children performed pulmonary function tests twice, and their parents reported the child's respiratory symptoms by self-administered questionnaires in both surveys.Results: The annual mean concentrations of air pollutants for the past 5 years for particulate matter less than 10 microns in diameter (PM 10), nitrogen (NO2), and sulfur dioxide (SO2) were respectively: 96.1 μg/m3, 76.0 μg/m3, and 65.7 μg/m3 in the highly-polluted district (HPD), 80.3 μg/m 3, 67.6 μg/m3, and 54.5 μg/m3 in the moderately-polluted district (MPD), and 80.0 μg/m3, 48.1 μg/m3, and 52.2 μg/m3 in the least-polluted district (LPD). After adjustment for potential confounders, significant deficits were found in the annual growth rates of forced expiratory flows at 25% (FEF 25), and between 25% and 75% (FEF25-75) in boys and FEF25 in girls (In boys, for FEF25, -0.136 l/s, p = 0.008 in MPD and -0.153 l/s, p = 0.004 in HPD, respectively; for FEF25-75, -0.176 l/s, p = 0.013 in MPD and -0.167 l/s, p = 0.021 in HPD, respectively. In girls, for FEF25, -0.123 l/s, p = 0.043 in HPD), using LPD as the reference. Deficits in the annual growth rate of forced expiratory volume in 1 s (FEV1) were also negatively associated with air pollution in boys (-0.063 L, p = 0.032 in HPD).Conclusions: The study adds more evidence that exposure to air pollution has adverse effects on lung function growth in schoolchildren.

AB - Objective: To evaluate the adverse effect of exposure to air pollution on lung function growth in school-aged children. Methods: A cohort of 1983 children from three districts in Guangzhou, China was followed-up for 6 months. The children performed pulmonary function tests twice, and their parents reported the child's respiratory symptoms by self-administered questionnaires in both surveys.Results: The annual mean concentrations of air pollutants for the past 5 years for particulate matter less than 10 microns in diameter (PM 10), nitrogen (NO2), and sulfur dioxide (SO2) were respectively: 96.1 μg/m3, 76.0 μg/m3, and 65.7 μg/m3 in the highly-polluted district (HPD), 80.3 μg/m 3, 67.6 μg/m3, and 54.5 μg/m3 in the moderately-polluted district (MPD), and 80.0 μg/m3, 48.1 μg/m3, and 52.2 μg/m3 in the least-polluted district (LPD). After adjustment for potential confounders, significant deficits were found in the annual growth rates of forced expiratory flows at 25% (FEF 25), and between 25% and 75% (FEF25-75) in boys and FEF25 in girls (In boys, for FEF25, -0.136 l/s, p = 0.008 in MPD and -0.153 l/s, p = 0.004 in HPD, respectively; for FEF25-75, -0.176 l/s, p = 0.013 in MPD and -0.167 l/s, p = 0.021 in HPD, respectively. In girls, for FEF25, -0.123 l/s, p = 0.043 in HPD), using LPD as the reference. Deficits in the annual growth rate of forced expiratory volume in 1 s (FEV1) were also negatively associated with air pollution in boys (-0.063 L, p = 0.032 in HPD).Conclusions: The study adds more evidence that exposure to air pollution has adverse effects on lung function growth in schoolchildren.

KW - Air pollution

KW - Children

KW - Cohort study

KW - Lung function growth

UR - https://www.scopus.com/pages/publications/77956343449

UR - https://www.sciencedirect.com/science/article/pii/S0954611110001952?via%3Dihub

U2 - 10.1016/j.rmed.2010.04.016

DO - 10.1016/j.rmed.2010.04.016

M3 - Journal article

C2 - 20471233

AN - SCOPUS:77956343449

SN - 0954-6111

VL - 104

SP - 1512

EP - 1520

JO - Respiratory Medicine

JF - Respiratory Medicine

IS - 10

ER -

Effects of ambient air pollution on lung function growth in Chinese schoolchildren

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