Effective treatment and prevention of attempted suicide, anxiety, and aggressiveness with fluoxetine, despite proven use of androgenic anabolic steroids

Julio M.X. Amaral*, Monica C. Padilha, Silvana V. Chagas, Julien BAKER, Carrie Mullen, Leonardo Vieira Neto, Francisco R. Aquino Neto, Marcelo S. Cruz

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The treatment of a man who attempted suicide after experiencing symptoms of anxiety and aggressiveness associated with the use of androgenic-anabolic steroids (AAS) is described. This report includes 30 days of inpatient treatment and a 6-month follow-up. Regular use of fluoxetine apparently prevented the onset of anxiety, depression, aggressiveness, and suicide ideation, even with the concurrent use of AAS. The urinary concentration of androgens, metabolites of AAS, and fluoxetine were monitored through analysis of urinary samples by the Brazilian Laboratory of Doping Control. Our results are congruent with previous findings describing the risk of suicide prompted by AAS use as well as the efficacy of fluoxetine in the treatment of mood disorders associated with the use of anabolic steroids.

Original languageEnglish
Pages (from-to)197-202
Number of pages6
JournalDrug Testing and Analysis
Volume13
Issue number1
DOIs
Publication statusPublished - Jan 2021

Scopus Subject Areas

  • Analytical Chemistry
  • Environmental Chemistry
  • Pharmaceutical Science
  • Spectroscopy

User-Defined Keywords

  • anabolic androgenic steroids
  • androgens
  • attempted suicide
  • mass spectrometry
  • performance-enhancing drugs

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