TY - JOUR
T1 - Effect of exercise as adjuvant to energy-restricted diets on quality of life and depression outcomes
T2 - a meta-analysis of randomized controlled trials
AU - Rajaie, Seyede Hamide
AU - Soltani, Sepideh
AU - Yazdanpanah, Zeinab
AU - Zohrabi, Tayebeh
AU - Beigrezaei, Sara
AU - Mohseni-Takalloo, Sahar
AU - Kaviani, Mojtaba
AU - Forbes, Scott C.
AU - Baker, Julien S.
AU - Salehi-Abargouei, Amin
N1 - Funding Information:
The current systematic review and meta-analysis was supported by the Research Council of the Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Funding Information:
We would like to thank the research council of Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences for their close cooperation and funding for the present study.
Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer Nature Switzerland AG.
PY - 2022/11
Y1 - 2022/11
N2 - Background and aim: Obesity and related co-morbidities lead to a decrease in health-related quality of life (HRQOL) and mood. Lifestyle strategies may improve these outcomes. However, the efficacy of exercise in conjunction with a weight-loss diet on HRQOL and mood is unclear. The aim of this systematic review and meta-analysis of randomized controlled trials (RCTs) was to examine whether the addition of exercise to energy-restricted dietary programs improves HRQOL and mood status when compared with energy-restricted diets alone in overweight and obese adults. Methods: Eligible RCTs were identified by searching PubMed/MEDLINE, EMBASE, ISI (Web of sciences), Scopus, and Google Scholar up to April 2021. Summary effects were derived using a random-effects model. The quality of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology. Results: The meta-analysis revealed that an energy-restricted diet plus exercise compared with an energy-restricted diet alone had no significant effects on depression (n = 6, hedges’g = − 0.04, 95% CI: − 0.28,0.20), MOS 36-Item Short-Form Health Survey (SF-36)-physical component summary scores (n = 8, weighted mean difference (WMD) = 1.51, 95% CI: − 0.16, 3.18), SF36-mental component summary scores (n = 7, WMD = 0.64, 95% CI: − 1.00, 2.28), and HRQOL disease-specific questionnaire scores (n = 5, hedges’g = 0.16, 95% CI: − 0.09, 0.40). The GRADE revealed that the quality of evidence was low for disease-specific HRQOL scores, and depression status; and high for physical and mental health assessed by SF-36. Conclusion: In our sample of overweight and obese adults, no beneficial effect of adding exercise to an energy-restricted diet was found in terms of HRQOL and Depression.
AB - Background and aim: Obesity and related co-morbidities lead to a decrease in health-related quality of life (HRQOL) and mood. Lifestyle strategies may improve these outcomes. However, the efficacy of exercise in conjunction with a weight-loss diet on HRQOL and mood is unclear. The aim of this systematic review and meta-analysis of randomized controlled trials (RCTs) was to examine whether the addition of exercise to energy-restricted dietary programs improves HRQOL and mood status when compared with energy-restricted diets alone in overweight and obese adults. Methods: Eligible RCTs were identified by searching PubMed/MEDLINE, EMBASE, ISI (Web of sciences), Scopus, and Google Scholar up to April 2021. Summary effects were derived using a random-effects model. The quality of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology. Results: The meta-analysis revealed that an energy-restricted diet plus exercise compared with an energy-restricted diet alone had no significant effects on depression (n = 6, hedges’g = − 0.04, 95% CI: − 0.28,0.20), MOS 36-Item Short-Form Health Survey (SF-36)-physical component summary scores (n = 8, weighted mean difference (WMD) = 1.51, 95% CI: − 0.16, 3.18), SF36-mental component summary scores (n = 7, WMD = 0.64, 95% CI: − 1.00, 2.28), and HRQOL disease-specific questionnaire scores (n = 5, hedges’g = 0.16, 95% CI: − 0.09, 0.40). The GRADE revealed that the quality of evidence was low for disease-specific HRQOL scores, and depression status; and high for physical and mental health assessed by SF-36. Conclusion: In our sample of overweight and obese adults, no beneficial effect of adding exercise to an energy-restricted diet was found in terms of HRQOL and Depression.
KW - Adults
KW - Aerobic
KW - Depression,mood
KW - Diet
KW - Exercise
KW - IVhet model
KW - Meta-analysis
KW - Obese
KW - Overweight
KW - Quality of life
KW - Randomized controlled trial
KW - Resistance
KW - Systematic review
KW - Weight loss
UR - http://www.scopus.com/inward/record.url?scp=85129484434&partnerID=8YFLogxK
U2 - 10.1007/s11136-022-03146-7
DO - 10.1007/s11136-022-03146-7
M3 - Review article
AN - SCOPUS:85129484434
SN - 0962-9343
VL - 31
SP - 3123
EP - 3137
JO - Quality of Life Research
JF - Quality of Life Research
IS - 11
ER -
