Early disruption of nerve mitochondrial and myelin lipid homeostasis in obesity-induced diabetes

Keyphrases

• Obesity 100%
• Nerve 100%
• Lipid Homeostasis 100%
• Mitochondrial Lipids 100%
• Myelin Lipids 100%
• Stress Diabetes 100%
• Diabetic Neuropathy 66%
• Diabetic 66%
• Neurological Complications 66%
• Myelin 66%
• Molecular Fingerprints 33%
• Insulin Resistance 33%
• Effective Therapy 33%
• Molecular Mechanism 33%
• Therapeutic Strategies 33%
• Hyperglycemia 33%
• Spatiotemporal 33%
• Diabetes 33%
• Substantial Evidence 33%
• Lipids 33%
• Lipid-lowering 33%
• Phosphatidylethanolamine 33%
• Lipidomics 33%
• Physiological Studies 33%
• Treatment Options 33%
• Biochemical Studies 33%
• Unmet Medical Need 33%
• Novel Lipids 33%
• Ultrastructural Study 33%
• Lipid-based 33%
• Glycemic Control 33%
• Distinct Subtypes 33%
• Major Complications 33%
• Obesity Treatment 33%
• Disease-modifying Therapy 33%
• Diabetes Complications 33%
• Current Treatment 33%
• CNS Tissue 33%
• Sulfatide 33%
• Plasmalogen 33%
• Non-obese Diabetic 33%
• Peripheral Neuropathy 33%
• Obesity Diabetes 33%
• Cardiolipin 33%
• Functional Defects 33%
• Nerve Damage 33%
• Lipid Abnormalities 33%
• α-galactosylceramide (α-GalCer) 33%
• Early Loss 33%

Neuroscience

• Myelin 100%
• Diabetes Mellitus 75%
• Diabetic Neuropathy 50%
• Hyperglycemia 25%
• Phosphatidylethanolamine 25%
• Galactosylceramide 25%
• Nerve Injury 25%
• Sulfatide 25%
• Plasmalogen 25%
• Neuropathy 25%
• Cardiolipin 25%