Dynamic sub-ontology evolution for traditional Chinese medicine web ontology

Yuxin Mao*, Zhaohui Wu, Wenya Tian, Xiaohong Jiang, Kwok Wai CHEUNG

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

19 Citations (Scopus)


As a form of important domain knowledge, large-scale ontologies play a critical role in building a large variety of knowledge-based systems. To overcome the problem of semantic heterogeneity and encode domain knowledge in reusable format, a large-scale and well-defined ontology is also required in the traditional Chinese medicine discipline. We argue that to meet the on-demand and scalability requirement ontology-based systems should go beyond the use of static ontology and be able to self-evolve and specialize for the domain knowledge they possess. In particular, we refer to the context-specific portions from large-scale ontologies like the traditional Chinese medicine ontology as sub-ontologies. Ontology-based systems are able to reuse sub-ontologies in local repository called ontology cache. In order to improve the overall performance of ontology cache, we propose to evolve sub-ontologies in ontology cache to optimize the knowledge structure of sub-ontologies. Moreover, we present the sub-ontology evolution approach based on a genetic algorithm for reusing large-scale ontologies. We evaluate the proposed evolution approach with the traditional Chinese medicine ontology and obtain promising results.

Original languageEnglish
Pages (from-to)790-805
Number of pages16
JournalJournal of Biomedical Informatics
Issue number5
Publication statusPublished - Oct 2008

Scopus Subject Areas

  • Computer Science Applications
  • Health Informatics

User-Defined Keywords

  • Evolutionary computation
  • Knowledge
  • Ontology
  • Sub-ontology
  • Traditional Chinese medicine


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