Abstract
The goal of this paper is to develop a double penalized hierarchical likelihood (DPHL) with a modified Cholesky decomposition for simultaneously selecting fixed and random effects in mixed effects models. DPHL avoids the use of data likelihood, which usually involves a high-dimensional integral, to define an objective function for variable selection. The resulting DPHL-based estimator enjoys the oracle properties with no requirement on the convexity of loss function. Moreover, a two-stage algorithm is proposed to effectively implement this approach. An H-likelihood-based Bayesian information criterion (BIC) is developed for tuning parameter selection. Simulated data and a real data set are examined to illustrate the efficiency of the proposed method.
Original language | English |
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Pages (from-to) | 108-128 |
Number of pages | 21 |
Journal | Statistics in Biosciences |
Volume | 7 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1 May 2015 |
Scopus Subject Areas
- Statistics and Probability
- Biochemistry, Genetics and Molecular Biology (miscellaneous)
User-Defined Keywords
- Hierarchical likelihood
- Mixed effects models
- Modified Cholesky decomposition
- Penalized likelihood
- Variable selection