TY - JOUR
T1 - DNA-T: Deformable Neighborhood Attention Transformer for Irregular Medical Time Series
AU - Huang, Jianxuan
AU - Yang, Baoyao
AU - Yin, Kejing
AU - Xu, Jingwen
N1 - This work was supported in part by the National Natural Science Foundation of China (NSFC) under Grant 62102098, in part by the Science and Technology Planning Project of Guangzhou under Grant 202201010266, in part by the National Natural Science Foundation of China (NSFC) under Grant 62302413, in part by the Natural Science Foundation of Guangdong Province under Grant 2024A1515010186, as well as Regional Joint Fund Project of Basic and Applied Basic Research Foundation of Guangdong Province under Grant 2022A1515140096.
Publisher Copyright:
© 2024 IEEE.
PY - 2024/7
Y1 - 2024/7
N2 - The real-world Electronic Health Records (EHRs) present irregularities due to changes in the patient's health status, resulting in various time intervals between observations and different physiological variables examined at each observation point. There have been recent applications of Transformer-based models in the field of irregular time series. However, the full attention mechanism in Transformer overly focuses on distant information, ignoring the short-term correlations of the condition. Thereby, the model is not able to capture localized changes or short-term fluctuations in patients' conditions. Therefore, we propose a novel end-to-end Deformable Neighborhood Attention Transformer (DNA-T) for irregular medical time series. The DNA-T captures local features by dynamically adjusting the receptive field of attention and aggregating relevant deformable neighborhoods in irregular time series. Specifically, we design a Deformable Neighborhood Attention (DNA) module that enables the network to attend to relevant neighborhoods by drifting the receiving field of neighborhood attention. The DNA enhances the model's sensitivity to local information and representation of local features, thereby capturing the correlation of localized changes in patients' conditions. We conduct extensive experiments to validate the effectiveness of DNA-T, outperforming existing state-of-the-art methods in predicting the mortality risk of patients. Moreover, we visualize an example to validate the effectiveness of the proposed DNA.
AB - The real-world Electronic Health Records (EHRs) present irregularities due to changes in the patient's health status, resulting in various time intervals between observations and different physiological variables examined at each observation point. There have been recent applications of Transformer-based models in the field of irregular time series. However, the full attention mechanism in Transformer overly focuses on distant information, ignoring the short-term correlations of the condition. Thereby, the model is not able to capture localized changes or short-term fluctuations in patients' conditions. Therefore, we propose a novel end-to-end Deformable Neighborhood Attention Transformer (DNA-T) for irregular medical time series. The DNA-T captures local features by dynamically adjusting the receptive field of attention and aggregating relevant deformable neighborhoods in irregular time series. Specifically, we design a Deformable Neighborhood Attention (DNA) module that enables the network to attend to relevant neighborhoods by drifting the receiving field of neighborhood attention. The DNA enhances the model's sensitivity to local information and representation of local features, thereby capturing the correlation of localized changes in patients' conditions. We conduct extensive experiments to validate the effectiveness of DNA-T, outperforming existing state-of-the-art methods in predicting the mortality risk of patients. Moreover, we visualize an example to validate the effectiveness of the proposed DNA.
KW - Deformable Neighborhood Attention
KW - Medical Time Series
KW - Transformer
UR - http://www.scopus.com/inward/record.url?scp=85192180153&partnerID=8YFLogxK
U2 - 10.1109/JBHI.2024.3395446
DO - 10.1109/JBHI.2024.3395446
M3 - Journal article
SN - 2168-2208
VL - 28
SP - 4224
EP - 4237
JO - IEEE Journal of Biomedical and Health Informatics
JF - IEEE Journal of Biomedical and Health Informatics
IS - 7
ER -