Diterpenoids from Isodon melissoides

Ai Hua Zhao, Quan Bin Han, Rong Tao Li, Sheng Hong Li, Chen Qing, Yan Li Zhang, Qin Shi Zhao, Fu Sheng Wang, Han Dong Sun*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

11 Citations (Scopus)


Nine new diterpenoids, melissoidesins M-U (1-9), along with five known analogues, melissoidesin F (10), xindongnin B (11), melissoidesin G (12), melissoidesin E (13), and dawoensin A (14), were isolated from the aerial parts of Isodon melissoides. The structures of new compounds were elucidated by analysis of spectral evidence including extensive 2D NMR data. Compounds 2, 3, 7, 11, 12, and 14 showed cytotoxicity against the human tumor BGC-823 cell line with IC50 values less than 10 μg/mL, respectively.

Original languageEnglish
Pages (from-to)1441-1444
Number of pages4
JournalJournal of Natural Products
Issue number9
Early online date31 Jul 2004
Publication statusPublished - 1 Sept 2004

Scopus Subject Areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry


Dive into the research topics of 'Diterpenoids from Isodon melissoides'. Together they form a unique fingerprint.

Cite this