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Keyphrases
Molecular Dynamics Simulation
100%
Pharmacophore Modeling
100%
Model Dynamics
100%
Combination Strategy
100%
ACAT2
100%
Deep Docking
100%
Inhibition Rate
33%
Acyl-CoA
33%
Lecithin-cholesterol Acyltransferase
33%
Molecular Mechanism
16%
Computational Approach
16%
Metabolism
16%
Inhibitory Activity
16%
Cholesterol
16%
Hypercholesterolemia
16%
Mouse Model
16%
Novel Scaffolds
16%
Selective Inhibition
16%
Esterification
16%
Enzyme Inhibition
16%
Ligand Binding
16%
Drug Design
16%
Atherosclerotic Lesions
16%
Enzyme Inhibitory Activity
16%
Screening Scheme
16%
ACAT1
16%
ACAT2-selective Inhibitor
16%
Intestinal Cholesterol Absorption
16%
Hotspot Residues
16%
Plasma Lipid Levels
16%
Virtual Screening Workflows
16%
Pharmacology, Toxicology and Pharmaceutical Science
Cholesterol Acyltransferase
100%
Pharmacophore Modeling
100%
Mouse Model
50%
Virtual Screening
50%
Hypercholesterolemia
50%
Drug Development
50%
Atherosclerosis
50%
Chemistry
Multilayer
100%
Acyl-CoA
100%
Molecular Dynamics Simulation
100%
Esterification
50%
Virtual Screening
50%
Ligand Binding
50%
Biochemistry, Genetics and Molecular Biology
ACAT2
100%
Pharmacophore Modeling
100%
Enzyme
42%
Absorption
28%
N-Acetyltransferase
28%
Acyl-CoA
28%
Mouse Model
14%
Esterification
14%
Metabolic Pathway
14%
Ligand Binding
14%
Blood Lipid
14%
Hypercholesterolemia
14%
Lipid Level
14%
Medicine and Dentistry
Pharmacophore
100%
Cholesterol Acyltransferase
100%
Virtual Screening
50%
Atherosclerosis
50%
Hypercholesterolemia
50%
Ligand Binding
50%