Dioxiranes generated in situ from pyruvates and oxone as environmentally friendly oxidizing agents for disinfection

Man-Kin Wong; Tak-Chung Chan; Wai-Yee Chan; Wing-Kei Chan; Lilian L.P. Vrijmoed; Desmond K. O'Toole; Chi-Ming Che

doi:10.1021/es050688l

Dioxiranes generated in situ from pyruvates and oxone as environmentally friendly oxidizing agents for disinfection

Man-Kin Wong^*, Tak-Chung Chan, Wai-Yee Chan, Wing-Kei Chan, Lilian L.P. Vrijmoed, Desmond K. O'Toole, Chi-Ming Che

^*Corresponding author for this work

Department of Biology

Research output: Contribution to journal › Journal article › peer-review

12 Citations (Scopus)

Abstract

Dioxiranes generated in situ from pyruvates (α-keto esters) and Oxone have been found to be environmentally friendly oxidizing agents for disinfection. These oxidizing agents were highly effective for destruction of various strains of bacteria, fungi, and bacterial endospores in a wide temperature range with exceptional stability. Notably, by using an aqueous solution of methyl pyruvate (1a) and Oxone/NaHCO₃, complete destruction of bacteria such as Staphylococcus aureusand fungus Penicillium corylophilum was achieved within 5 min at 20 °C at neutral pH. Highly chemical-resistant bacterial endospores of Bacillus cereus could also be destroyed. The high antibacterial activity of 1a could be attributed to its strong electron-withdrawing α-ester group.

Original language	English
Pages (from-to)	625-630
Number of pages	6
Journal	Environmental Science and Technology
Volume	40
Issue number	2
DOIs	https://doi.org/10.1021/es050688l
Publication status	Published - 15 Jan 2006

Scopus Subject Areas

Chemistry(all)
Environmental Chemistry

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1021/es050688l

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@article{c13c7e82cc8d48d3900f8452f4b4947e,

title = "Dioxiranes generated in situ from pyruvates and oxone as environmentally friendly oxidizing agents for disinfection",

abstract = "Dioxiranes generated in situ from pyruvates (α-keto esters) and Oxone have been found to be environmentally friendly oxidizing agents for disinfection. These oxidizing agents were highly effective for destruction of various strains of bacteria, fungi, and bacterial endospores in a wide temperature range with exceptional stability. Notably, by using an aqueous solution of methyl pyruvate (1a) and Oxone/NaHCO3, complete destruction of bacteria such as Staphylococcus aureusand fungus Penicillium corylophilum was achieved within 5 min at 20 °C at neutral pH. Highly chemical-resistant bacterial endospores of Bacillus cereus could also be destroyed. The high antibacterial activity of 1a could be attributed to its strong electron-withdrawing α-ester group.",

author = "Man-Kin Wong and Tak-Chung Chan and Wai-Yee Chan and Wing-Kei Chan and Vrijmoed, {Lilian L.P.} and O'Toole, {Desmond K.} and Chi-Ming Che",

note = "This work was supported by the HKU Seed Funding for Applied Research, The University of Hong Kong (University Development Fund), the Hong Kong Research Grants Council (HKU7384/02P), and the Area of Excellence Scheme (AoE/P-10-01) established under the University Grants Committee (HKSAR). ",

year = "2006",

month = jan,

day = "15",

doi = "10.1021/es050688l",

language = "English",

volume = "40",

pages = "625--630",

journal = "Environmental Science and Technology",

issn = "0013-936X",

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T1 - Dioxiranes generated in situ from pyruvates and oxone as environmentally friendly oxidizing agents for disinfection

AU - Wong, Man-Kin

AU - Chan, Tak-Chung

AU - Chan, Wai-Yee

AU - Chan, Wing-Kei

AU - Vrijmoed, Lilian L.P.

AU - O'Toole, Desmond K.

AU - Che, Chi-Ming

N1 - This work was supported by the HKU Seed Funding for Applied Research, The University of Hong Kong (University Development Fund), the Hong Kong Research Grants Council (HKU7384/02P), and the Area of Excellence Scheme (AoE/P-10-01) established under the University Grants Committee (HKSAR).

PY - 2006/1/15

Y1 - 2006/1/15

N2 - Dioxiranes generated in situ from pyruvates (α-keto esters) and Oxone have been found to be environmentally friendly oxidizing agents for disinfection. These oxidizing agents were highly effective for destruction of various strains of bacteria, fungi, and bacterial endospores in a wide temperature range with exceptional stability. Notably, by using an aqueous solution of methyl pyruvate (1a) and Oxone/NaHCO3, complete destruction of bacteria such as Staphylococcus aureusand fungus Penicillium corylophilum was achieved within 5 min at 20 °C at neutral pH. Highly chemical-resistant bacterial endospores of Bacillus cereus could also be destroyed. The high antibacterial activity of 1a could be attributed to its strong electron-withdrawing α-ester group.

AB - Dioxiranes generated in situ from pyruvates (α-keto esters) and Oxone have been found to be environmentally friendly oxidizing agents for disinfection. These oxidizing agents were highly effective for destruction of various strains of bacteria, fungi, and bacterial endospores in a wide temperature range with exceptional stability. Notably, by using an aqueous solution of methyl pyruvate (1a) and Oxone/NaHCO3, complete destruction of bacteria such as Staphylococcus aureusand fungus Penicillium corylophilum was achieved within 5 min at 20 °C at neutral pH. Highly chemical-resistant bacterial endospores of Bacillus cereus could also be destroyed. The high antibacterial activity of 1a could be attributed to its strong electron-withdrawing α-ester group.

UR - http://www.scopus.com/inward/record.url?scp=31144457506&partnerID=8YFLogxK

U2 - 10.1021/es050688l

DO - 10.1021/es050688l

M3 - Journal article

C2 - 16468412

AN - SCOPUS:31144457506

SN - 0013-936X

VL - 40

SP - 625

EP - 630

JO - Environmental Science and Technology

JF - Environmental Science and Technology

IS - 2

ER -

Dioxiranes generated in situ from pyruvates and oxone as environmentally friendly oxidizing agents for disinfection

Abstract

Scopus Subject Areas

UN SDGs

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