Differentiation of Rhizoma et Radix Polygoni Cuspidati from closely related herbs by HPLC fingerprinting

Guangsheng Qian, Sik Yuen Leung, L. U. Guanghua, Kelvin S Y LEUNG*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

An HPLC-DAD fingerprinting profile of Rhizoma Et Radix Polygoni Cuspidati was established basing on the consistent chromatographic features of 24 authentic herb samples. The major types of chemical constituents, stilbenes and anthraquinones, were analyzed and included in the fingerprint. Eight common peaks of Polygonum Cuspidatum were identified by using HPLC-MS. The developed fingerprint was applied to differentiate Rhizoma Et Radix Polygoni Cuspidati from Radix Polygoni Multiflori and Radix Et Rhizoma Rhei. Although the three herbs belong to the family of Polygonaceae, the results indicated that these could be differentiated by using the established method.

Original languageEnglish
Pages (from-to)1179-1186
Number of pages8
JournalChemical and Pharmaceutical Bulletin
Volume54
Issue number8
DOIs
Publication statusPublished - 2006

Scopus Subject Areas

  • Chemistry(all)
  • Drug Discovery

User-Defined Keywords

  • Fingerprint
  • HPLC-DAD-MS
  • Polygonaceae
  • Quality control
  • Rhizoma Et Radix Polygoni Cuspidati

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