Differentiation of Rhizoma et Radix Polygoni Cuspidati from closely related herbs by HPLC fingerprinting

Guangsheng Qian; Sik Yuen Leung; L. U. Guanghua; Kelvin S Y LEUNG

doi:10.1248/cpb.54.1179

Differentiation of Rhizoma et Radix Polygoni Cuspidati from closely related herbs by HPLC fingerprinting

Guangsheng Qian, Sik Yuen Leung, L. U. Guanghua, Kelvin S Y LEUNG^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › peer-review

22 Citations (Scopus)

Abstract

An HPLC-DAD fingerprinting profile of Rhizoma Et Radix Polygoni Cuspidati was established basing on the consistent chromatographic features of 24 authentic herb samples. The major types of chemical constituents, stilbenes and anthraquinones, were analyzed and included in the fingerprint. Eight common peaks of Polygonum Cuspidatum were identified by using HPLC-MS. The developed fingerprint was applied to differentiate Rhizoma Et Radix Polygoni Cuspidati from Radix Polygoni Multiflori and Radix Et Rhizoma Rhei. Although the three herbs belong to the family of Polygonaceae, the results indicated that these could be differentiated by using the established method.

Original language	English
Pages (from-to)	1179-1186
Number of pages	8
Journal	Chemical and Pharmaceutical Bulletin
Volume	54
Issue number	8
DOIs	https://doi.org/10.1248/cpb.54.1179
Publication status	Published - 2006

Scopus Subject Areas

General Chemistry
Drug Discovery

User-Defined Keywords

Fingerprint
HPLC-DAD-MS
Polygonaceae
Quality control
Rhizoma Et Radix Polygoni Cuspidati

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10.1248/cpb.54.1179

Cite this

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title = "Differentiation of Rhizoma et Radix Polygoni Cuspidati from closely related herbs by HPLC fingerprinting",

abstract = "An HPLC-DAD fingerprinting profile of Rhizoma Et Radix Polygoni Cuspidati was established basing on the consistent chromatographic features of 24 authentic herb samples. The major types of chemical constituents, stilbenes and anthraquinones, were analyzed and included in the fingerprint. Eight common peaks of Polygonum Cuspidatum were identified by using HPLC-MS. The developed fingerprint was applied to differentiate Rhizoma Et Radix Polygoni Cuspidati from Radix Polygoni Multiflori and Radix Et Rhizoma Rhei. Although the three herbs belong to the family of Polygonaceae, the results indicated that these could be differentiated by using the established method.",

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AU - Qian, Guangsheng

AU - Leung, Sik Yuen

AU - Guanghua, L. U.

AU - LEUNG, Kelvin S Y

PY - 2006

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AB - An HPLC-DAD fingerprinting profile of Rhizoma Et Radix Polygoni Cuspidati was established basing on the consistent chromatographic features of 24 authentic herb samples. The major types of chemical constituents, stilbenes and anthraquinones, were analyzed and included in the fingerprint. Eight common peaks of Polygonum Cuspidatum were identified by using HPLC-MS. The developed fingerprint was applied to differentiate Rhizoma Et Radix Polygoni Cuspidati from Radix Polygoni Multiflori and Radix Et Rhizoma Rhei. Although the three herbs belong to the family of Polygonaceae, the results indicated that these could be differentiated by using the established method.

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Differentiation of Rhizoma et Radix Polygoni Cuspidati from closely related herbs by HPLC fingerprinting

Abstract

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