Dietary Calcium Decreases Plasma Cholesterol Level only in Female but not in Male Hamster Fed a High Cholesterol Diet

  • Ka Ying Ma
  • , Yin Tong Liang
  • , Jing Nan Chen
  • , Yue Jiang
  • , Kin Ming Kwan
  • , Cheng Peng
  • , Rui Jiao
  • , Yuan Yuan Zuo
  • , Yu Huang
  • , Zhen Yu Chen*
  • *Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

3 Citations (Scopus)

Abstract

Objective:

To investigate the effect of dietary calcium on plasma lipoprotein profile in castrated and ovariectomized hamsters. 

Methods:

Male, castrated, female and ovariectomized hamsters (n=36 each group) were randomly divided into three sub-groups (n=12) and fed one of the three diets containing 0, 2, and 8 g calcium per kg diet for a period of six weeks. Changes in plasma lipoprotein profile were monitored at the end of week 0, 3 and 6.

Results:

Plasma total cholesterol (TC), non-high density lipoprotein cholesterol (non-HDL-C), triacylglycerols (TG) and TC/HDL-C were decreased only in intact female and ovariectomized hamsters. In contrast, three levels of dietary calcium had no effect on lipoprotein profiles in both intact male and castrated hamsters.

Conclusion:

Beneficial modification of lipoprotein profile by dietary calcium was gender-dependent at least in hamsters.

Original languageEnglish
Pages (from-to)392-398
Number of pages7
JournalBiomedical and Environmental Sciences
Volume25
Issue number4
DOIs
Publication statusPublished - Aug 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

User-Defined Keywords

  • Calcium
  • Cholesterol
  • Fecal sterols
  • Triacylglycerols

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