Dietary Calcium Decreases Plasma Cholesterol Level only in Female but not in Male Hamster Fed a High Cholesterol Diet

Ka Ying Ma; Yin Tong Liang; Jing Nan Chen; Yue Jiang; Kin Ming Kwan; Cheng Peng; Rui Jiao; Yuan Yuan Zuo; Yu Huang; Zhen Yu Chen

doi:10.3967/0895-3988.2012.04.003

Dietary Calcium Decreases Plasma Cholesterol Level only in Female but not in Male Hamster Fed a High Cholesterol Diet

Ka Ying Ma, Yin Tong Liang, Jing Nan Chen, Yue Jiang, Kin Ming Kwan, Cheng Peng, Rui Jiao, Yuan Yuan Zuo, Yu Huang, Zhen Yu Chen^*

^*Corresponding author for this work

Department of Biology

Research output: Contribution to journal › Journal article › peer-review

3 Citations (Scopus)

Abstract

Objective:

To investigate the effect of dietary calcium on plasma lipoprotein profile in castrated and ovariectomized hamsters.

Methods:

Male, castrated, female and ovariectomized hamsters (n=36 each group) were randomly divided into three sub-groups (n=12) and fed one of the three diets containing 0, 2, and 8 g calcium per kg diet for a period of six weeks. Changes in plasma lipoprotein profile were monitored at the end of week 0, 3 and 6.

Results:

Plasma total cholesterol (TC), non-high density lipoprotein cholesterol (non-HDL-C), triacylglycerols (TG) and TC/HDL-C were decreased only in intact female and ovariectomized hamsters. In contrast, three levels of dietary calcium had no effect on lipoprotein profiles in both intact male and castrated hamsters.

Conclusion:

Beneficial modification of lipoprotein profile by dietary calcium was gender-dependent at least in hamsters.

Original language	English
Pages (from-to)	392-398
Number of pages	7
Journal	Biomedical and Environmental Sciences
Volume	25
Issue number	4
DOIs	https://doi.org/10.3967/0895-3988.2012.04.003
Publication status	Published - Aug 2012

User-Defined Keywords

Calcium
Cholesterol
Fecal sterols
Triacylglycerols

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3967/0895-3988.2012.04.003

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@article{55bf0e668f8c4309ba176b90b09d8a4e,

title = "Dietary Calcium Decreases Plasma Cholesterol Level only in Female but not in Male Hamster Fed a High Cholesterol Diet",

abstract = "Objective:To investigate the effect of dietary calcium on plasma lipoprotein profile in castrated and ovariectomized hamsters. Methods:Male, castrated, female and ovariectomized hamsters (n=36 each group) were randomly divided into three sub-groups (n=12) and fed one of the three diets containing 0, 2, and 8 g calcium per kg diet for a period of six weeks. Changes in plasma lipoprotein profile were monitored at the end of week 0, 3 and 6.Results:Plasma total cholesterol (TC), non-high density lipoprotein cholesterol (non-HDL-C), triacylglycerols (TG) and TC/HDL-C were decreased only in intact female and ovariectomized hamsters. In contrast, three levels of dietary calcium had no effect on lipoprotein profiles in both intact male and castrated hamsters.Conclusion:Beneficial modification of lipoprotein profile by dietary calcium was gender-dependent at least in hamsters.",

keywords = "Calcium, Cholesterol, Fecal sterols, Triacylglycerols",

author = "Ma, {Ka Ying} and Liang, {Yin Tong} and Chen, {Jing Nan} and Yue Jiang and Kwan, {Kin Ming} and Cheng Peng and Rui Jiao and Zuo, {Yuan Yuan} and Yu Huang and Chen, {Zhen Yu}",

note = "This work was supported by a grant from Hong Kong Research Grant Council (CUHK 4622/08M). Publisher copyright: {\textcopyright} 2012 by China CDC",

year = "2012",

month = aug,

doi = "10.3967/0895-3988.2012.04.003",

language = "English",

volume = "25",

pages = "392--398",

journal = "Biomedical and Environmental Sciences",

issn = "0895-3988",

publisher = "Elsevier Ltd.",

number = "4",

}

TY - JOUR

T1 - Dietary Calcium Decreases Plasma Cholesterol Level only in Female but not in Male Hamster Fed a High Cholesterol Diet

AU - Ma, Ka Ying

AU - Liang, Yin Tong

AU - Chen, Jing Nan

AU - Jiang, Yue

AU - Kwan, Kin Ming

AU - Peng, Cheng

AU - Jiao, Rui

AU - Zuo, Yuan Yuan

AU - Huang, Yu

AU - Chen, Zhen Yu

PY - 2012/8

Y1 - 2012/8

N2 - Objective:To investigate the effect of dietary calcium on plasma lipoprotein profile in castrated and ovariectomized hamsters. Methods:Male, castrated, female and ovariectomized hamsters (n=36 each group) were randomly divided into three sub-groups (n=12) and fed one of the three diets containing 0, 2, and 8 g calcium per kg diet for a period of six weeks. Changes in plasma lipoprotein profile were monitored at the end of week 0, 3 and 6.Results:Plasma total cholesterol (TC), non-high density lipoprotein cholesterol (non-HDL-C), triacylglycerols (TG) and TC/HDL-C were decreased only in intact female and ovariectomized hamsters. In contrast, three levels of dietary calcium had no effect on lipoprotein profiles in both intact male and castrated hamsters.Conclusion:Beneficial modification of lipoprotein profile by dietary calcium was gender-dependent at least in hamsters.

AB - Objective:To investigate the effect of dietary calcium on plasma lipoprotein profile in castrated and ovariectomized hamsters. Methods:Male, castrated, female and ovariectomized hamsters (n=36 each group) were randomly divided into three sub-groups (n=12) and fed one of the three diets containing 0, 2, and 8 g calcium per kg diet for a period of six weeks. Changes in plasma lipoprotein profile were monitored at the end of week 0, 3 and 6.Results:Plasma total cholesterol (TC), non-high density lipoprotein cholesterol (non-HDL-C), triacylglycerols (TG) and TC/HDL-C were decreased only in intact female and ovariectomized hamsters. In contrast, three levels of dietary calcium had no effect on lipoprotein profiles in both intact male and castrated hamsters.Conclusion:Beneficial modification of lipoprotein profile by dietary calcium was gender-dependent at least in hamsters.

KW - Calcium

KW - Cholesterol

KW - Fecal sterols

KW - Triacylglycerols

UR - http://www.scopus.com/inward/record.url?scp=84867011257&partnerID=8YFLogxK

U2 - 10.3967/0895-3988.2012.04.003

DO - 10.3967/0895-3988.2012.04.003

M3 - Journal article

C2 - 23026518

AN - SCOPUS:84867011257

SN - 0895-3988

VL - 25

SP - 392

EP - 398

JO - Biomedical and Environmental Sciences

JF - Biomedical and Environmental Sciences

IS - 4

ER -

Dietary Calcium Decreases Plasma Cholesterol Level only in Female but not in Male Hamster Fed a High Cholesterol Diet

Abstract

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