Developing clinical practice guidelines for the integration of Chinese medicine and biomedicine: A new process

Nannan Shi, Linda L.D. Zhong, Chi Zhang, Xuejie Han, Yuexi Wang, Yuqi Liu, Liying Wang, Mengyu Liu, Aiping LYU*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

1 Citation (Scopus)


Introduction Despite the integration of Chinese medicine and biomedicine which has emerged in clinical practice worldwide, a comprehensive development process for clinical practice guidelines (CPG) has up to now been missing. A valid method for the rational use of predictions for herb-drug interaction is a biggest challenge in guideline development process. Methods This article summarises the development process by reviewing key literature from CPG developers. It focuseson key methods and challenges specific to CPGs for integration by using text mining and bioinformatics to provide a powerful adjunct to CPG development. Results The guideline development process identified, together with new approaches, incorporates evidence-based methodology and provides better decisions through analysis of uncertain herb-drug interaction. Conclusions This new process used three basic phases (preparation, development, and finalization) and seven steps providing a set of methodological principles for CPG development intergrating Chinese medicine and biomedicine.

Original languageEnglish
Pages (from-to)916-920
Number of pages5
JournalEuropean Journal of Integrative Medicine
Issue number6
Publication statusPublished - 1 Dec 2016

Scopus Subject Areas

  • Complementary and alternative medicine

User-Defined Keywords

  • Biomedicine
  • Chinese medicine
  • Clinical practice guideline
  • Methodology


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