TY - JOUR
T1 - Detecting low-brominated diphenyl ethers by highly sensitive biosensors based on the blocking effect on glucose oxidase
AU - Jiang, Xuerui
AU - Bai, Xiaoyun
AU - Liu, Xiaohui
AU - Wang, Xuemei
AU - Shiu, Kwok Keung
N1 - This work was supported by the Partner State Key Laboratory of Environmental and Biological Analysis of Hong Kong Baptist University (SKLP/14-15/P007), the National Natural Science Foundation of China (Grant No. 82061148012, 82027806), and the National High Technology Research & Development Program of China (2017YFA0205300).
Publisher Copyright:
© 2023 The Author(s). Published by the Royal Society of Chemistry.
PY - 2023/1/1
Y1 - 2023/1/1
N2 - Low-brominated diphenyl ether, whose species have an average of 1-4 bromine atoms per molecule, have attracted more and more attention for their high risk of dioxin formation in combustion and effective bioaccumulation in humans and wildlife. Therefore, it is crucial to monitor the level of low-brominated diphenyl ethers. In this study, we fabricated a novel GOD~/AuNPs#rGO-CHIT/GC electrode to realize the direct electron transfer of glucose oxidase (GOD) for the determination of BDE-15 based on the blocking effect. The results indicated that the as-prepared GOD~/AuNPs#rGO-CHIT/GC electrode can be used for the sensitive detection of two low-brominated diphenyl ethers through the blocking effect on GOD. The linear range for the detection of BDE-15 was 0.2-8 µM, with a sensitivity of 2.86 µA µM-1 cm-2, and the relevant limits of detection of the two target analytes were 0.14 µM (S/N = 3), respectively. This rapid, highly sensitive and cost-effective detection method was also applied to the detection of BDE-3, BDE-28, and BDE-47, which could potentially be used to monitor the levels of PBDEs in our living environment.
AB - Low-brominated diphenyl ether, whose species have an average of 1-4 bromine atoms per molecule, have attracted more and more attention for their high risk of dioxin formation in combustion and effective bioaccumulation in humans and wildlife. Therefore, it is crucial to monitor the level of low-brominated diphenyl ethers. In this study, we fabricated a novel GOD~/AuNPs#rGO-CHIT/GC electrode to realize the direct electron transfer of glucose oxidase (GOD) for the determination of BDE-15 based on the blocking effect. The results indicated that the as-prepared GOD~/AuNPs#rGO-CHIT/GC electrode can be used for the sensitive detection of two low-brominated diphenyl ethers through the blocking effect on GOD. The linear range for the detection of BDE-15 was 0.2-8 µM, with a sensitivity of 2.86 µA µM-1 cm-2, and the relevant limits of detection of the two target analytes were 0.14 µM (S/N = 3), respectively. This rapid, highly sensitive and cost-effective detection method was also applied to the detection of BDE-3, BDE-28, and BDE-47, which could potentially be used to monitor the levels of PBDEs in our living environment.
UR - http://www.scopus.com/inward/record.url?scp=85170713115&partnerID=8YFLogxK
UR - https://pubs.rsc.org/en/content/articlelanding/2023/sd/d2sd00161f
U2 - 10.1039/d2sd00161f
DO - 10.1039/d2sd00161f
M3 - Journal article
AN - SCOPUS:85170713115
SN - 2635-0998
VL - 2
SP - 176
EP - 187
JO - Sensors and Diagnostics
JF - Sensors and Diagnostics
IS - 1
ER -
