Daily intake and human risk assessment of organochlorine pesticides (OCPs) based on Cambodian market basket data

Hong Sheng Wang, Suthipong Sthiannopkao, Jun Du, Zhuo Jia Chen, Kyoung Woong Kim, Mohamed Salleh Mohamed Yasin, Jamal Hisham Hashim, Chris K C WONG, Ming Hung WONG*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

102 Citations (Scopus)


To assess organochlorine pesticide (OCP) contaminations and its possible adverse health impacts, different food samples were collected from three areas of Cambodia, one of the poorest countries in the world. The ∑OCP concentrations in Kampong Cham, Kratie and Kandal provinces ranged from 1.28 to 188 (median 3.11), 1.06 to 25.1 (5.59) and 2.20 to 103 (20.6)ngg -1, respectively. The dichlorodiphenyltrichloroethanes (DDTs) were the predominant OCPs and accounted for 62.2% (median) among all foodstuffs. Congener profile analyses suggested that there were new input sources of DDTs and hexachlorocyclohexanes (HCHs) in Cambodia, particularly in Kandal province. The estimated daily intake of OCPs (330ngkg -1day -1) for residents in Kandal province ranked No. 1 among the 13 compared countries or regions. On the basis of 95th percentile concentrations, the carcinogenic hazard ratios (HRs) of most investigated individual OCPs in vegetable and fish in Cambodia exceeding unity. Particularly for α-HCH in vegetable, the 95th HR was as high as 186. The data revealed that there is a great cancer risk for the local residents with life time consumption of OCP contaminated vegetable and fish. To our knowledge, this the first study to evaluate the daily intakes of OCPs in Cambodia.

Original languageEnglish
Pages (from-to)1441-1449
Number of pages9
JournalJournal of Hazardous Materials
Issue number3
Publication statusPublished - 15 Sept 2011

Scopus Subject Areas

  • Environmental Engineering
  • Environmental Chemistry
  • Waste Management and Disposal
  • Pollution
  • Health, Toxicology and Mutagenesis

User-Defined Keywords

  • Cambodia
  • Daily intake
  • Food consumption
  • Organochlorine pesticides (OCPs)
  • Risk assessment


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