TY - JOUR
T1 - Daily intake and human risk assessment of organochlorine pesticides (OCPs) based on Cambodian market basket data
AU - Wang, Hong Sheng
AU - Sthiannopkao, Suthipong
AU - Du, Jun
AU - Chen, Zhuo Jia
AU - Kim, Kyoung Woong
AU - Mohamed Yasin, Mohamed Salleh
AU - Hashim, Jamal Hisham
AU - Wong, Chris Kong Chu
AU - Wong, Ming Hung
N1 - Funding Information:
The authors thank International Environmental Research Center, Gwangju Institute of Science and Technology, Republic of Korea, United Nations University-International Institute for Global Health, Malaysia, Mr. Kongkea Phan, Mr. Vibol Sao, Dr. H.M. Leung and Mr. K.W. Chan for technical assistance, and Dr. G.H. Xing for supervising the food consumption survey. This research was supported by the Research Grants Council of the University Grants Committee of Hong Kong (Collaborative Research Fund, HKBU1/CRF/08 and Special Equipment Grant, HKBU09 ), and the Mini-AOE (Area of Excellence) Fund from Hong Kong Baptist University .
PY - 2011/9/15
Y1 - 2011/9/15
N2 - To assess organochlorine pesticide (OCP) contaminations and its possible adverse health impacts, different food samples were collected from three areas of Cambodia, one of the poorest countries in the world. The ∑OCP concentrations in Kampong Cham, Kratie and Kandal provinces ranged from 1.28 to 188 (median 3.11), 1.06 to 25.1 (5.59) and 2.20 to 103 (20.6)ngg -1, respectively. The dichlorodiphenyltrichloroethanes (DDTs) were the predominant OCPs and accounted for 62.2% (median) among all foodstuffs. Congener profile analyses suggested that there were new input sources of DDTs and hexachlorocyclohexanes (HCHs) in Cambodia, particularly in Kandal province. The estimated daily intake of OCPs (330ngkg -1day -1) for residents in Kandal province ranked No. 1 among the 13 compared countries or regions. On the basis of 95th percentile concentrations, the carcinogenic hazard ratios (HRs) of most investigated individual OCPs in vegetable and fish in Cambodia exceeding unity. Particularly for α-HCH in vegetable, the 95th HR was as high as 186. The data revealed that there is a great cancer risk for the local residents with life time consumption of OCP contaminated vegetable and fish. To our knowledge, this the first study to evaluate the daily intakes of OCPs in Cambodia.
AB - To assess organochlorine pesticide (OCP) contaminations and its possible adverse health impacts, different food samples were collected from three areas of Cambodia, one of the poorest countries in the world. The ∑OCP concentrations in Kampong Cham, Kratie and Kandal provinces ranged from 1.28 to 188 (median 3.11), 1.06 to 25.1 (5.59) and 2.20 to 103 (20.6)ngg -1, respectively. The dichlorodiphenyltrichloroethanes (DDTs) were the predominant OCPs and accounted for 62.2% (median) among all foodstuffs. Congener profile analyses suggested that there were new input sources of DDTs and hexachlorocyclohexanes (HCHs) in Cambodia, particularly in Kandal province. The estimated daily intake of OCPs (330ngkg -1day -1) for residents in Kandal province ranked No. 1 among the 13 compared countries or regions. On the basis of 95th percentile concentrations, the carcinogenic hazard ratios (HRs) of most investigated individual OCPs in vegetable and fish in Cambodia exceeding unity. Particularly for α-HCH in vegetable, the 95th HR was as high as 186. The data revealed that there is a great cancer risk for the local residents with life time consumption of OCP contaminated vegetable and fish. To our knowledge, this the first study to evaluate the daily intakes of OCPs in Cambodia.
KW - Cambodia
KW - Daily intake
KW - Food consumption
KW - Organochlorine pesticides (OCPs)
KW - Risk assessment
UR - http://www.scopus.com/inward/record.url?scp=80052023094&partnerID=8YFLogxK
U2 - 10.1016/j.jhazmat.2011.06.062
DO - 10.1016/j.jhazmat.2011.06.062
M3 - Journal article
C2 - 21764512
AN - SCOPUS:80052023094
SN - 0304-3894
VL - 192
SP - 1441
EP - 1449
JO - Journal of Hazardous Materials
JF - Journal of Hazardous Materials
IS - 3
ER -
