Cytotoxic hydrolyzable tannins from Balanophora japonica

Zhi Hong Jiang; Xiao Yun Wen; Takashi Tanaka; Shao Yu Wu; Zhongqiu Liu; Hiromi Iwata; Yoko Hirose; Shuguang Wu; Isao Kouno

doi:10.1021/np070519+

Cytotoxic hydrolyzable tannins from Balanophora japonica

Zhi Hong Jiang^*
, Xiao Yun Wen
, Takashi Tanaka
, Shao Yu Wu
, Zhongqiu Liu
, Hiromi Iwata
, Yoko Hirose
, Shuguang Wu
, Isao Kouno

^*Corresponding author for this work

School of Chinese Medicine

Research output: Contribution to journal › Journal article › peer-review

31 Citations (Scopus)

Abstract

Four hydrolyzable tannins named balanophotannins D-G (1-4) were isolated from the aerial parts of the parasitic plant Balanophora japonica. Their structures were characterized on the basis of spectroscopic and chemical evidence. Balanophotannins D-G contain an oxidized hexahydroxydiphenoyl (HHDP) group. The absolute configurations of balanophotannins D (1) and F (3) were determined via the PGME method. Balanophotannin E (2) showed cytotoxicity to Hep G2 cancer cells with an IC₅₀ value of 4.22 μM.

Original language	English
Pages (from-to)	719-723
Number of pages	5
Journal	Journal of Natural Products
Volume	71
Issue number	4
DOIs	https://doi.org/10.1021/np070519+
Publication status	Published - Apr 2008

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title = "Cytotoxic hydrolyzable tannins from Balanophora japonica",

abstract = "Four hydrolyzable tannins named balanophotannins D-G (1-4) were isolated from the aerial parts of the parasitic plant Balanophora japonica. Their structures were characterized on the basis of spectroscopic and chemical evidence. Balanophotannins D-G contain an oxidized hexahydroxydiphenoyl (HHDP) group. The absolute configurations of balanophotannins D (1) and F (3) were determined via the PGME method. Balanophotannin E (2) showed cytotoxicity to Hep G2 cancer cells with an IC50 value of 4.22 μM.",

author = "Jiang, \{Zhi Hong\} and Wen, \{Xiao Yun\} and Takashi Tanaka and Wu, \{Shao Yu\} and Zhongqiu Liu and Hiromi Iwata and Yoko Hirose and Shuguang Wu and Isao Kouno",

note = "Financial support from the Department of Science and Technology of Guangzhou in China (Grant No. 2006Z1-E6021) is gratefully acknowledged. ",

year = "2008",

month = apr,

doi = "10.1021/np070519+",

language = "English",

volume = "71",

pages = "719--723",

journal = "Journal of Natural Products",

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TY - JOUR

T1 - Cytotoxic hydrolyzable tannins from Balanophora japonica

AU - Jiang, Zhi Hong

AU - Wen, Xiao Yun

AU - Tanaka, Takashi

AU - Wu, Shao Yu

AU - Liu, Zhongqiu

AU - Iwata, Hiromi

AU - Hirose, Yoko

AU - Wu, Shuguang

AU - Kouno, Isao

N1 - Financial support from the Department of Science and Technology of Guangzhou in China (Grant No. 2006Z1-E6021) is gratefully acknowledged.

PY - 2008/4

Y1 - 2008/4

N2 - Four hydrolyzable tannins named balanophotannins D-G (1-4) were isolated from the aerial parts of the parasitic plant Balanophora japonica. Their structures were characterized on the basis of spectroscopic and chemical evidence. Balanophotannins D-G contain an oxidized hexahydroxydiphenoyl (HHDP) group. The absolute configurations of balanophotannins D (1) and F (3) were determined via the PGME method. Balanophotannin E (2) showed cytotoxicity to Hep G2 cancer cells with an IC50 value of 4.22 μM.

AB - Four hydrolyzable tannins named balanophotannins D-G (1-4) were isolated from the aerial parts of the parasitic plant Balanophora japonica. Their structures were characterized on the basis of spectroscopic and chemical evidence. Balanophotannins D-G contain an oxidized hexahydroxydiphenoyl (HHDP) group. The absolute configurations of balanophotannins D (1) and F (3) were determined via the PGME method. Balanophotannin E (2) showed cytotoxicity to Hep G2 cancer cells with an IC50 value of 4.22 μM.

UR - https://www.scopus.com/pages/publications/43249103930

U2 - 10.1021/np070519+

DO - 10.1021/np070519+

M3 - Journal article

C2 - 18302336

AN - SCOPUS:43249103930

SN - 0163-3864

VL - 71

SP - 719

EP - 723

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 4

ER -

Cytotoxic hydrolyzable tannins from Balanophora japonica

Abstract

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