Cytotoxic hydrolyzable tannins from Balanophora japonica

Zhi Hong JIANG*, Xiao Yun Wen, Takashi Tanaka, Shao Yu Wu, Zhongqiu Liu, Hiromi Iwata, Yoko Hirose, Shuguang Wu, Isao Kouno

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)

Abstract

Four hydrolyzable tannins named balanophotannins D-G (1-4) were isolated from the aerial parts of the parasitic plant Balanophora japonica. Their structures were characterized on the basis of spectroscopic and chemical evidence. Balanophotannins D-G contain an oxidized hexahydroxydiphenoyl (HHDP) group. The absolute configurations of balanophotannins D (1) and F (3) were determined via the PGME method. Balanophotannin E (2) showed cytotoxicity to Hep G2 cancer cells with an IC50 value of 4.22 μM.

Original languageEnglish
Pages (from-to)719-723
Number of pages5
JournalJournal of Natural Products
Volume71
Issue number4
DOIs
Publication statusPublished - Apr 2008

Scopus Subject Areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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