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Cytoprotective effect of 20(S)-Rg3 on benzo[a]pyrene-induced DNA damage
Po Ying Poon
, Hoi Hin Kwok
,
Patrick Y K YUE
, Mildred S.M. Yang
, Nai Ki MAK
,
Chris K C WONG
, Ricky N S WONG
*
*
Corresponding author for this work
Department of Biology
Research output
:
Contribution to journal
›
Journal article
›
peer-review
32
Citations (Scopus)
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Dive into the research topics of 'Cytoprotective effect of 20(S)-Rg3 on benzo[a]pyrene-induced DNA damage'. Together they form a unique fingerprint.
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Keyphrases
DNA Damage
100%
Benzo(a)pyrene
100%
20(S)-Rg3
100%
Ginsenoside
33%
Pregnane X Receptor
33%
Protective Effect
22%
Ginseng
22%
20(S)-ginsenoside Rg3
22%
Gene Expression
11%
Panax Ginseng C. A. Meyer
11%
Chinese Medicinal Herbs
11%
HepG2 Cells
11%
Small Interfering RNA (siRNA)
11%
Comet Assay
11%
Human Cells
11%
Knockdown
11%
Polycyclic Aromatic Hydrocarbons
11%
Mechanistic Studies
11%
Active Constituents
11%
Human Dermal Fibroblasts
11%
Receptor Expression
11%
Nuclear Factor Erythroid 2-related Factor 2 (Nrf2)
11%
Nuclear Translocation
11%
Tail Moment
11%
Co-treatment
11%
Phosphoinositide 3-kinase (PI3K)
11%
Genotoxicity
11%
Bifunctional Ligand
11%
Environmental Carcinogens
11%
Nuclear Receptor
11%
Ginseng Extract
11%
Nrf2 Pathway
11%
Genotoxic Effect
11%
NQO1
11%
Cytoprotective Agents
11%
Human Dermal Fibroblast Cells
11%
Phase II Enzymes
11%
Protein Kinase B/Akt
11%
Drug Clearance
11%
Cellular Dysfunction
11%
Pharmacology, Toxicology and Pharmaceutical Science
Benzo(a)pyrene
100%
Cytoprotective Agent
100%
Ginseng
33%
Transcription Factor Nrf2
33%
Pregnane X Receptor
33%
Small Interfering RNA
11%
Comet Assay
11%
Polycyclic Aromatic Hydrocarbon
11%
Protein Kinase B
11%
Cell Nucleus Receptor
11%
Phosphatidylinositol 3 Kinase
11%
Ginseng Extract
11%
Oxidoreductase
11%
Genotoxicity
11%
Carcinogen
11%