Cyclometalated Platinum(II) Complexes as Highly Sensitive Luminescent Switch-On Probes for Practical Application in Protein Staining and Cell Imaging

Peng Wu; Ella Lai-Ming Wong; Dik-Lung Ma; Glenna So-Ming Tong; Kwan-Ming Ng; Chi-Ming Che

doi:10.1002/chem.200802707

Cyclometalated Platinum(II) Complexes as Highly Sensitive Luminescent Switch-On Probes for Practical Application in Protein Staining and Cell Imaging

Peng Wu, Ella Lai-Ming Wong, Dik-Lung Ma, Glenna So-Ming Tong, Kwan-Ming Ng, Chi-Ming Che^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

142 Citations (Scopus)

Abstract

Protein-staining platinum: The luminescent switch-on characteristic of the platinum(II) complex can be utilized for staining a series of proteins in sodium dodecyl sulfate-polyarcylamide gels, to give emissive gel images directly under UV light (see figure). The detection sensitivity for BSA protein is down to 6.0 ng, revealing potential practical applications of luminescent platinum(II) complexes in the luminescent signaling of biomolecules.

Original language	English
Pages (from-to)	3652-3656
Number of pages	5
Journal	Chemistry - A European Journal
Volume	15
Issue number	15
DOIs	https://doi.org/10.1002/chem.200802707
Publication status	Published - 6 Apr 2009

Scopus Subject Areas

Catalysis
Organic Chemistry

User-Defined Keywords

Cell imaging
Gels
Luminescence
Noncovalent interactions
Platinum
Protein staining

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10.1002/chem.200802707

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abstract = "Protein-staining platinum: The luminescent switch-on characteristic of the platinum(II) complex can be utilized for staining a series of proteins in sodium dodecyl sulfate-polyarcylamide gels, to give emissive gel images directly under UV light (see figure). The detection sensitivity for BSA protein is down to 6.0 ng, revealing potential practical applications of luminescent platinum(II) complexes in the luminescent signaling of biomolecules. ",

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AU - Tong, Glenna So-Ming

AU - Ng, Kwan-Ming

AU - Che, Chi-Ming

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Cyclometalated Platinum(II) Complexes as Highly Sensitive Luminescent Switch-On Probes for Practical Application in Protein Staining and Cell Imaging

Abstract

Scopus Subject Areas

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