@article{568d13a3da5a43b2a2692fe5f8082aaa,
title = "Cyclometalated gold(iii) complexes with N-heterocyclic carbene ligands as topoisomerase i poisons",
abstract = "A panel of stable [Au(R-CNC)(N-heterocyclic carbene)]+ complexes displays prominent in vitro anticancer properties; [Au(CNC)(IMe)]CF 3SO3 (1, IMe = 1,3-dimethylimidazol-2-ylidene) significantly poisons topoisomerase I in vitro and suppresses tumor growth in nude mice model.",
author = "Yan, {Jessie Jing} and Chow, {Andy Lok Fung} and Leung, {Chung Hang} and Sun, {Raymond Wai Yin} and MA, {Edmond Dik Lung} and Che, {Chi Ming}",
note = "We acknowledge the support from the University of Hong Kong (University Development Fund) and the Area of Excellence Scheme (AoE/P-10/01) administered by the University Grants Committee (HKSAR, China).",
year = "2010",
month = jun,
day = "14",
doi = "10.1039/c001216e",
language = "English",
volume = "46",
pages = "3893--3895",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "22",
}