@article{b11314f467a24a50a916c4538f79bd81,
title = "Cyanines as new fluorescent probes for DNA detection and two-photon excited bioimaging",
abstract = "A series of cyanine fluorophores based on fused aromatics as an electron donor for DNA sensing and two-photon bioimaging were synthesized, among which the carbazole-based biscyanine exhibits high sensitivity and efficiency as a fluorescent light-up probe for dsDNA, which shows selective binding toward the AT-rich regions. The synergetic effect of the bischromophoric skeleton gives a several-fold enhancement in a two-photon absorption cross-section as well as a 25- to 100-fold enhancement in two-photon excited fluorescence upon dsDNA binding.",
author = "Feng, {Xin Jiang} and Wu, {Po Lam} and Fr{\'e}d{\'e}ric Bolze and Leung, {Heidi W.C.} and Li, {King Fai} and MAK, {Nai Ki} and KWONG, {Daniel W J} and Nicoud, {Jean Fran{\c c}ois} and CHEAH, {Kok Wai} and WONG, {Ricky M S}",
note = "This work was financially supported by Hong Kong Research Grant Council, GRF, HKBU 202408, Hong Kong Baptist University, the Faculty Research Grant, FRG/08-09/II-16, and the PROCORE-France/Hong Kong Joint Research Scheme sponsored by the Research Grants Council of Hong Kong and the Consulate General of France in Hong Kong, F-HK04/07T. L. Richert and Y. M{\'e}ly at UdS are acknowledged for two-photon microscopy experiments. ",
year = "2010",
month = may,
day = "21",
doi = "10.1021/ol100474b",
language = "English",
volume = "12",
pages = "2194--2197",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "10",
}