Current evidence for the hepatoprotective activities of the medicinal mushroom Antrodia cinnamomea

Patrick Ying Kit Yue; Yi Yi Wong; Kay Yuen Ki Wong; Yeuk Ki Tsoi; Kelvin Sze Yin Leung

doi:10.1186/1749-8546-8-21

Current evidence for the hepatoprotective activities of the medicinal mushroom Antrodia cinnamomea

Patrick Ying Kit Yue^*, Yi Yi Wong, Kay Yuen Ki Wong, Yeuk Ki Tsoi, Kelvin Sze Yin Leung

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

28 Citations (Scopus)

Abstract

Antrodia cinnamomea (AC) is an endemic mushroom species of Taiwan, and has been demonstrated to possess diverse biological and pharmacological activities, such as anti-hypertension, anti-hyperlipidemia, anti-inflammation, anti-oxidation, anti-tumor, and immunomodulation. This review focuses on the inhibitory effects of AC on hepatitis, hepatocarcinoma, and alcohol-induced liver diseases (e.g., fatty liver, fibrosis). The relevant biochemical and molecular mechanisms are addressed. Overall, this review summarizes the hepatoprotective activities in vitro and in vivo. However, there is no doubt that human and clinical trials are still limited, and further studies are required for the development of AC-related products.

Original language	English
Article number	21
Journal	Chinese Medicine
Volume	8
Issue number	1
DOIs	https://doi.org/10.1186/1749-8546-8-21
Publication status	Published - 1 Nov 2013

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title = "Current evidence for the hepatoprotective activities of the medicinal mushroom Antrodia cinnamomea",

abstract = "Antrodia cinnamomea (AC) is an endemic mushroom species of Taiwan, and has been demonstrated to possess diverse biological and pharmacological activities, such as anti-hypertension, anti-hyperlipidemia, anti-inflammation, anti-oxidation, anti-tumor, and immunomodulation. This review focuses on the inhibitory effects of AC on hepatitis, hepatocarcinoma, and alcohol-induced liver diseases (e.g., fatty liver, fibrosis). The relevant biochemical and molecular mechanisms are addressed. Overall, this review summarizes the hepatoprotective activities in vitro and in vivo. However, there is no doubt that human and clinical trials are still limited, and further studies are required for the development of AC-related products.",

author = "Yue, {Patrick Ying Kit} and Wong, {Yi Yi} and Wong, {Kay Yuen Ki} and Tsoi, {Yeuk Ki} and Leung, {Kelvin Sze Yin}",

note = "K.S.Y. Leung would like to thank the Hong Kong Baptist University for financial support.",

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AU - Yue, Patrick Ying Kit

AU - Wong, Yi Yi

AU - Wong, Kay Yuen Ki

AU - Tsoi, Yeuk Ki

AU - Leung, Kelvin Sze Yin

N1 - K.S.Y. Leung would like to thank the Hong Kong Baptist University for financial support.

PY - 2013/11/1

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N2 - Antrodia cinnamomea (AC) is an endemic mushroom species of Taiwan, and has been demonstrated to possess diverse biological and pharmacological activities, such as anti-hypertension, anti-hyperlipidemia, anti-inflammation, anti-oxidation, anti-tumor, and immunomodulation. This review focuses on the inhibitory effects of AC on hepatitis, hepatocarcinoma, and alcohol-induced liver diseases (e.g., fatty liver, fibrosis). The relevant biochemical and molecular mechanisms are addressed. Overall, this review summarizes the hepatoprotective activities in vitro and in vivo. However, there is no doubt that human and clinical trials are still limited, and further studies are required for the development of AC-related products.

AB - Antrodia cinnamomea (AC) is an endemic mushroom species of Taiwan, and has been demonstrated to possess diverse biological and pharmacological activities, such as anti-hypertension, anti-hyperlipidemia, anti-inflammation, anti-oxidation, anti-tumor, and immunomodulation. This review focuses on the inhibitory effects of AC on hepatitis, hepatocarcinoma, and alcohol-induced liver diseases (e.g., fatty liver, fibrosis). The relevant biochemical and molecular mechanisms are addressed. Overall, this review summarizes the hepatoprotective activities in vitro and in vivo. However, there is no doubt that human and clinical trials are still limited, and further studies are required for the development of AC-related products.

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JO - Chinese Medicine

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Current evidence for the hepatoprotective activities of the medicinal mushroom Antrodia cinnamomea

Abstract

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