Current evidence for the hepatoprotective activities of the medicinal mushroom Antrodia cinnamomea

Patrick Y K YUE*, Yi Yi Wong, Kay Yuen Ki Wong, Yeuk Ki Tsoi, Kelvin S Y LEUNG

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

15 Citations (Scopus)

Abstract

Antrodia cinnamomea (AC) is an endemic mushroom species of Taiwan, and has been demonstrated to possess diverse biological and pharmacological activities, such as anti-hypertension, anti-hyperlipidemia, anti-inflammation, anti-oxidation, anti-tumor, and immunomodulation. This review focuses on the inhibitory effects of AC on hepatitis, hepatocarcinoma, and alcohol-induced liver diseases (e.g., fatty liver, fibrosis). The relevant biochemical and molecular mechanisms are addressed. Overall, this review summarizes the hepatoprotective activities in vitro and in vivo. However, there is no doubt that human and clinical trials are still limited, and further studies are required for the development of AC-related products.

Original languageEnglish
Article number21
JournalChinese Medicine
Volume8
Issue number1
DOIs
Publication statusPublished - 1 Nov 2013

Scopus Subject Areas

  • Pharmacology
  • Complementary and alternative medicine

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