Critical review on the research of chemical structure, bioactivities, and mechanism of actions of Dendrobium officinale polysaccharide

Cheuk Hei Lai, Chu Ying Huo, Jun Xu, Quan Bin Han, Li Feng Li*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

1 Citation (Scopus)

Abstract

Dendrobium officinale (Tie-Pi-Shi-Hu) is a precious traditional Chinese medicine (TCM). The principal active components are polysaccharides (DOP), which have a high potency in therapeutic applications. However, limitations in structure analysis and underlying mechanism investigation impede its further research. This review systemically and critically summarises current understanding in both areas, and points out the influence of starch impurities and the role of gut microbiota in DOP research. As challenges faced in studying natural polysaccharide investigations are common, this review contributes to a broader understanding of polysaccharides beyond DOP.
Original languageEnglish
Article number130315
Number of pages12
JournalInternational Journal of Biological Macromolecules
Volume263
Early online date19 Feb 2024
DOIs
Publication statusPublished - Apr 2024

Scopus Subject Areas

  • Structural Biology
  • Biochemistry
  • Molecular Biology

User-Defined Keywords

  • Bioactivity
  • Dendrobium officinale
  • Gut microbiota
  • Polysaccharides
  • Structure analysis

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