@article{9fe915e9438d4ad5a223b4396334ea7e,
title = "Critical review on the research of chemical structure, bioactivities, and mechanism of actions of Dendrobium officinale polysaccharide",
abstract = "Dendrobium officinale (Tie-Pi-Shi-Hu) is a precious traditional Chinese medicine (TCM). The principal active components are polysaccharides (DOP), which have a high potency in therapeutic applications. However, limitations in structure analysis and underlying mechanism investigation impede its further research. This review systemically and critically summarises current understanding in both areas, and points out the influence of starch impurities and the role of gut microbiota in DOP research. As challenges faced in studying natural polysaccharide investigations are common, this review contributes to a broader understanding of polysaccharides beyond DOP.",
keywords = "Bioactivity, Dendrobium officinale, Gut microbiota, Polysaccharides, Structure analysis",
author = "Lai, {Cheuk Hei} and Huo, {Chu Ying} and Jun Xu and Han, {Quan Bin} and Li, {Li Feng}",
note = "Funding information: This work was funded and supported by HKSAR Innovation and Technology Fund (ITF), Tier 3, ITS/311/09, General Research Fund (12100615, 22100014, 12100818, 12101322, 12101123), UGC Research Matching Grant Scheme (2019-1-10, 2019-1-14, 2019-2-06), Health Medical Research Fund (11122531, 14150521, 17182681), National Natural Science Foundation of China (81473341, 82173948, 82204747), the Science and Technology Project of Shenzhen (JCYJ20160531193812867), the Key-Area Research and Development Program of Guangdong Province (2020B1111110007), Hong Kong Baptist University (RC-Start-up Grants, MPCF-001-2016/2017, RC-IRMS/14-15/06, FRG2/17-18/060 and FRG2/16-17/002), and Vincent & Lily Woo Foundation. Publisher Copyright: {\textcopyright} 2024 Elsevier B.V.",
year = "2024",
month = apr,
doi = "10.1016/j.ijbiomac.2024.130315",
language = "English",
volume = "263",
journal = "International Journal of Biological Macromolecules",
issn = "0141-8130",
publisher = "Elsevier",
}