Critical design factors for optical imaging with metal coordination complexes

David Parker

doi:10.1071/CH10365

Critical design factors for optical imaging with metal coordination complexes

David Parker^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

37 Citations (Scopus)

Abstract

Metal coordination complexes are emerging as an important class of optical imaging probes. They may function not only as stains for particular cell compartments, but also as responsive probes, able to report on changes in local ionic composition. The critical factors to consider in designing such probes are reviewed, including issues of cell uptake and compartmentalization, the degree of non-invasiveness and their functional performance. Prospects are considered for the development of lanthanide(iii) probes capable of reporting changes in local bicarbonate, citrate, and lactate.

Original language	English
Pages (from-to)	239-243
Number of pages	5
Journal	Australian Journal of Chemistry
Volume	64
Issue number	3
DOIs	https://doi.org/10.1071/CH10365
Publication status	Published - 11 Mar 2011
Event	39th International Conference on Coordination Chemistry - Adelaide Convention Centre, Adelaide, Australia Duration: 25 Jul 2010 → 30 Jul 2010 https://www.rsc.org/events/detail/4401/39th-international-conference-on-coordination-chemistry (Conference website) https://www.publish.csiro.au/ch/issue/5615 (Conference proceeding)

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1071/CH10365

Cite this

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abstract = "Metal coordination complexes are emerging as an important class of optical imaging probes. They may function not only as stains for particular cell compartments, but also as responsive probes, able to report on changes in local ionic composition. The critical factors to consider in designing such probes are reviewed, including issues of cell uptake and compartmentalization, the degree of non-invasiveness and their functional performance. Prospects are considered for the development of lanthanide(iii) probes capable of reporting changes in local bicarbonate, citrate, and lactate.",

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year = "2011",

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doi = "10.1071/CH10365",

language = "English",

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N2 - Metal coordination complexes are emerging as an important class of optical imaging probes. They may function not only as stains for particular cell compartments, but also as responsive probes, able to report on changes in local ionic composition. The critical factors to consider in designing such probes are reviewed, including issues of cell uptake and compartmentalization, the degree of non-invasiveness and their functional performance. Prospects are considered for the development of lanthanide(iii) probes capable of reporting changes in local bicarbonate, citrate, and lactate.

AB - Metal coordination complexes are emerging as an important class of optical imaging probes. They may function not only as stains for particular cell compartments, but also as responsive probes, able to report on changes in local ionic composition. The critical factors to consider in designing such probes are reviewed, including issues of cell uptake and compartmentalization, the degree of non-invasiveness and their functional performance. Prospects are considered for the development of lanthanide(iii) probes capable of reporting changes in local bicarbonate, citrate, and lactate.

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UR - https://www.publish.csiro.au/ch/CH10365

U2 - 10.1071/CH10365

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AN - SCOPUS:79952856834

SN - 0004-9425

VL - 64

SP - 239

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JO - Australian Journal of Chemistry

JF - Australian Journal of Chemistry

IS - 3

T2 - 39th International Conference on Coordination Chemistry

Y2 - 25 July 2010 through 30 July 2010

ER -

Critical design factors for optical imaging with metal coordination complexes

Abstract

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