Translated title of the contribution: Heavy-atom effect of Corrole photosensitizer for photodynamic therapy

刘海洋*, 郭平叶, 江柏荣, 应晓, 廖世军, 麦乃歧, 张启光

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

16 Citations (Scopus)


最近,我们合成了一系列Corrole衍生物,经过鼻咽癌(Nasopharyngeal carcinoma,NPC) 细胞的体外PDT试验后,筛选出了一个具有优良PDT活性的Corrole光敏剂。本文报道该类Corrole光敏剂在PDT中的重原子效应。

10-(2-Hydroxylphenyl)-5,15-bis(pentafluorophenyl) corrole was found to have a remarkable photocytotoxicity on nasopharyngeal carcinoma(NPC) cell line(Chang C. K. et al., Proc SPIE, 2006, Vol. 6139, p268). To explore the heavy-atom effect on corrole photosensitizer, an exact analogue of corole 1 with the modification of two heavy iodine atoms on its 10-phenyl group, 10-(2-hydroxyl-3,5-diiodophenyl)-5,15-bis(pentafluorophenyl)corrole, were synthesized.

Translated title of the contributionHeavy-atom effect of Corrole photosensitizer for photodynamic therapy
Original languageChinese (Simplified)
Pages (from-to)1363-1365
Number of pages3
Issue number7
Publication statusPublished - 10 Jul 2006

Scopus Subject Areas

  • Chemistry(all)

User-Defined Keywords

  • 光敏剂
  • 鼻咽癌
  • 光动力治疗
  • 重原子效应
  • Corrole
  • Photosensitizer
  • Nasopharyngeal carcinoma
  • Photodynamic therapy
  • Heavy-atom effect


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