Controllable Synthesis of Hollow Microtubular Covalent Organic Frameworks as an Enzyme-Immobilized Platform for Enhancing Catalytic Activity

Chao Zhong, Wende Ma, Yanting He, Dan Ouyang, Guorong Li, Yixin Yang, Qiong Zheng, Huan Huang, Zongwei Cai, Zian Lin*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

28 Citations (Scopus)

Abstract

Despite great achievement that has been made in the synthesis of covalent organic frameworks (COFs), precise construction of COFs with well-defined nano/microstructures poses a rigorous challenge. Herein, we introduce a simple template-free strategy for controllable synthesis of hollow microtubular COFs. The obtained COFs show a spontaneous morphology transformation from a microfiber to a hollow microtubular structure when the concentrations of catalytic acid are regulated elaborately. Furthermore, the as-prepared COFs exhibit high crystallinity, well-defined hollow tubular morphology, and high surface areas (μ2600 m2/g). Taking the advantages of the unique morphological structure, the hollow microtubular COFs can serve as an ideal host material for enzymes. The resultant biocomposites show high catalytic performance and can be successfully applied to rapid and high-efficiency proteolysis of proteins. This work blazes a trail for controllable synthesis of the hollow microtubular COFs through a template-free process and expands the application of COFs as a promising platform for enzyme immobilization.

Original languageEnglish
Pages (from-to)52417-52424
Number of pages8
JournalACS Applied Materials and Interfaces
Volume13
Issue number44
Early online date1 Nov 2021
DOIs
Publication statusPublished - 10 Nov 2021

Scopus Subject Areas

  • Materials Science(all)

User-Defined Keywords

  • controllable synthesis
  • covalent organic frameworks
  • enzyme immobilization
  • hollow microtube
  • proteomics

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