Construction of a pH-driven supramolecular nanovalve

Thoi D. Nguyen, Ken C.F. Leung, Monty Liong, Cari D. Pentecost, J. Fraser Stoddart*, Jeffrey I. Zink

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

232 Citations (Scopus)


The versatility of supramolecular chemistry has been exploited in constructing nanovalves based on mesoporous silica MCM-41 and the mutual recognition between secondary dialkylammonium ions and dibenzo[24]crown-8 (DB24C8). Naphthalene-containing dialkylammonium threads were tethered to the MCM-41, followed by loading with coumarin 460 and capping with DB24C8. Controlled release of coumarin 460 from the pores of MCM-41 was demonstrated using different bases. The rate of release of coumarin 460 from the nanovalves depends on the size of the base.

Original languageEnglish
Pages (from-to)3363-3366
Number of pages4
JournalOrganic Letters
Issue number15
Publication statusPublished - 20 Jul 2006

Scopus Subject Areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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