Construction of a Nano Biosensor for Cyanide Anion Detection and Its Application in Environmental and Biological Systems

Zhen Zhen Dong, Chao Yang, Kasipandi Vellaisamy, Guodong Li, Chung Hang Leung*, Edmond Dik Lung MA

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

We have developed a Ag@Au core-shell nanoparticle (NP)/iridium(III) complex-based sensing platform for the sensitive luminescence "turn-on" sensing of cyanide ions, an acutely toxic pollutant. The assay is based on the quenching effect of Ag@Au NPs on the emission of complex 1, but luminescence is restored after the addition of cyanide anions due to their ability to dissolve the Au shell. Our sensing platform exhibited a high sensitivity toward cyanide anions with a detection limit of 0.036 μM, and also showed high selectivity for cyanide over 10-fold excess amounts of other anions. The sensing platform was also successfully applied to monitor cyanide anions in drinking water and in living cells.

Original languageEnglish
Pages (from-to)1517-1522
Number of pages6
JournalACS Sensors
Volume2
Issue number10
DOIs
Publication statusPublished - 27 Oct 2017

Scopus Subject Areas

  • Bioengineering
  • Instrumentation
  • Process Chemistry and Technology
  • Fluid Flow and Transfer Processes

User-Defined Keywords

  • Ag@Au core-shell nanoparticle
  • cell imaging
  • cyanide
  • drinking water
  • iridium(III) complex

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