@article{44aee97a1ae7420789e717cbbc8758a6,
title = "Construction of a Nano Biosensor for Cyanide Anion Detection and Its Application in Environmental and Biological Systems",
abstract = "We have developed a Ag@Au core-shell nanoparticle (NP)/iridium(III) complex-based sensing platform for the sensitive luminescence {"}turn-on{"} sensing of cyanide ions, an acutely toxic pollutant. The assay is based on the quenching effect of Ag@Au NPs on the emission of complex 1, but luminescence is restored after the addition of cyanide anions due to their ability to dissolve the Au shell. Our sensing platform exhibited a high sensitivity toward cyanide anions with a detection limit of 0.036 μM, and also showed high selectivity for cyanide over 10-fold excess amounts of other anions. The sensing platform was also successfully applied to monitor cyanide anions in drinking water and in living cells.",
keywords = "Ag@Au core-shell nanoparticle, cell imaging, cyanide, drinking water, iridium(III) complex",
author = "Dong, {Zhen Zhen} and Chao Yang and Kasipandi Vellaisamy and Guodong Li and Leung, {Chung Hang} and Ma, {Dik Lung}",
note = "Funding Information: This work is supported by Hong Kong Baptist University (FRG2/16-17/007), the Health and Medical Research Fund (HMRF/14130522), the Research Grants Council (HKBU/ 12301115 and HKBU/201913), the National Natural Science Foundation of China (21575121), the Guangdong Province Natural Science Foundation (2015A030313816), the Hong Kong Baptist University Century Club Sponsorship Scheme 2016, the Interdisciplinary Research Matching Scheme (RC-IRMS/14-15/06), Innovation and Technology Fund (ITS/ 260/16FX), Matching Proof of Concept Fund (MPCF-001-2017/18), the Science and Technology Development Fund, Macao SAR (077/2016/A2 and 007/2014/AMJ), the University of Macau (MYRG2015-00137-ICMS-QRCM, MYRG2016-00151-ICMS-QRCM, and MRG044/LCH/2015/ ICMS), National Natural Science Foundation of China (21628502).",
year = "2017",
month = oct,
day = "27",
doi = "10.1021/acssensors.7b00553",
language = "English",
volume = "2",
pages = "1517--1522",
journal = "ACS Sensors",
issn = "2379-3694",
publisher = "American Chemical Society",
number = "10",
}
