@article{77ec9ff1aec0480e9ee82b2946b39360,
title = "Concise Synthesis of Natural Phenylphenalenone Phytoalexins and a Regioisomer",
abstract = "Concise total syntheses of the natural phytoalexins 2-hydroxy-8-(4-hydroxyphenyl)phenalen-1-one (1), 2-hydroxy-8-(3,4-dihydroxyphenyl)phenalen-1-one (2), and hydroxyanigorufone (4), together with regioisomer 3 are accomplished in 11 or 12 steps. The synthetic strategy features a Friedel-Crafts acylation to construct the 1H-phenalen-1-one tricyclic core followed by a Suzuki cross-coupling to obtain the target compounds.",
author = "Wang, \{Ming Zhong\} and Ku, \{Chuen Fai\} and Si, \{Tong Xu\} and Tsang, \{Siu Wai\} and Lv, \{Xiao Meng\} and Li, \{Xiao Wan\} and Li, \{Zheng Ming\} and Hongjie Zhang and Chan, \{Albert S C\}",
note = "Funding Information: This work was financially supported by the Research Foundation for Advanced Talents (36000-18821101); Guangdong Natural Science Foundation (2017A030313751); the Fundamental Research Funds for the Central Universities (16ykpy33) of Sun Yat-sen University, Guangzhou, China; the Medical Scientific Research Foundation of Guangdong Province (A2016090); the Science and Technology Planning Project of Guangzhou City (201707010189), Hong Kong Scholars Program (XJ2013025), China; and the Interdisciplinary Research Matching Scheme (RC-IRMS/15-16/02) of Hong Kong Baptist University, Hong Kong SAR, China.",
year = "2018",
month = jan,
day = "26",
doi = "10.1021/acs.jnatprod.7b00709",
language = "English",
volume = "81",
pages = "98--105",
journal = "Journal of Natural Products",
issn = "0163-3864",
publisher = "American Chemical Society",
number = "1",
}