Concentrations and congener profiles of polybrominated diphenyl ethers (PBDEs) in blood plasma from Hong Kong: Implications for sources and exposure route

Hong Sheng Wang*, Guan Min Jiang, Zhuo Jia Chen, Jun Du, Yu Bon Man, John P. Giesy, Chris K C WONG, Ming Hung WONG

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

33 Citations (Scopus)

Abstract

There was limited information about bioaccumulation of polybrominated diphenyl ethers (PBDEs) in humans of the general population of Hong Kong. Therefore, the present study was conducted to determine concentrations and congener profiles of PBDEs in blood plasma from Hong Kong, evaluate their sources and correlations with other organobrominated compounds, and investigate exposure routes from fish and dust. Concentrations of ∑PBDE22 ranged from 0.56 to 92ngg-1, lipid weight (lw), with a median of 5.4ngg-1. BDE-47 was the dominant congener, accounting for 26% of ∑PBDE22. Concentrations of PBDE congeners in market fish were significantly (r2=0.89, p<0.001) correlated with plasma. Positive but no significant correlations were observed, between concentrations of PBDE congeners in indoor dust from workplaces (r2=0.46, p=0.081) and homes (r2=0.49, p=0.10), with concentrations of PBDE in human blood plasma. The results indicated that dietary exposure, particularly consumption of fish, is a major pathway through which people in Hong Kong are exposed to PBDEs. Furthermore, our data revealed a spatial distribution and terrestrial source of BDE-28 for local people. Results of the present study, which was the first systematic study to investigate concentrations of PBDEs in blood of Hong Kong people, provides useful information to which future measurements can be compared.

Original languageEnglish
Pages (from-to)253-259
Number of pages7
JournalJournal of Hazardous Materials
Volume261
DOIs
Publication statusPublished - 5 Oct 2013

Scopus Subject Areas

  • Environmental Engineering
  • Environmental Chemistry
  • Waste Management and Disposal
  • Pollution
  • Health, Toxicology and Mutagenesis

User-Defined Keywords

  • Bioaccumulation
  • Dust
  • Fish
  • PBDEs
  • Plasma

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